Literature DB >> 25079146

Towards the Development of Smart 3D "gated scaffolds" for on-command delivery.

Núria Mas1, Daniel Arcos, Lorena Polo, Elena Aznar, Sandra Sánchez-Salcedo, Félix Sancenón, Ana García, M Dolores Marcos, Alejandro Baeza, María Vallet-Regí, Ramón Martínez-Máñez.   

Abstract

A new approach towards the design of "gated scaffolds" based on the combination of capped mesoporous silica nanoparticles (MSNs) with porous biomaterials is reported. Using this approach, a 3D gelatin-based scaffold able to selectively deliver cargo in the presence of an APase enzyme is prepared and tested. This new design opens up the possibility of developing new smart biomaterials with advanced drug-delivery features.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  3D scaffolds; biomaterials; controlled release; mesoporous silica nanoparticles

Mesh：

Substances：

Year:  2014        PMID： 25079146     DOI： 10.1002/smll.201401227

Source DB:  PubMed          Journal:  Small        ISSN： 1613-6810            Impact factor:   13.281


  7 in total

1.  Development of a three-dimensional cell culture system based on microfluidics for nuclear magnetic resonance and optical monitoring.

Authors:  Vicent Esteve; Javier Berganzo; Rosa Monge; M Carmen Martínez-Bisbal; Rosa Villa; Bernardo Celda; Luis Fernandez
Journal:  Biomicrofluidics       Date:  2014-11-18       Impact factor: 2.800

Review 2.  Biomaterials against Bone Infection.

Authors:  María Vallet-Regí; Daniel Lozano; Blanca González; Isabel Izquierdo-Barba
Journal:  Adv Healthc Mater       Date:  2020-05-25       Impact factor: 9.933

Review 3.  Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

Authors:  María Vallet-Regí; Ferdi Schüth; Daniel Lozano; Montserrat Colilla; Miguel Manzano
Journal:  Chem Soc Rev       Date:  2022-07-04       Impact factor: 60.615

Review 4.  Smart Mesoporous Nanomaterials for Antitumor Therapy.

Authors:  Marina Martínez-Carmona; Montserrat Colilla; Maria Vallet-Regí
Journal:  Nanomaterials (Basel)       Date:  2015-11-06       Impact factor: 5.076

Review 5.  Mesoporous Silica Nanoparticles for Drug Delivery: Current Insights.

Authors:  María Vallet-Regí; Montserrat Colilla; Isabel Izquierdo-Barba; Miguel Manzano
Journal:  Molecules       Date:  2017-12-25       Impact factor: 4.411

6.  pH-Dependent Molecular Gate Mesoporous Microparticles for Biological Control of Giardia intestinalis.

Authors:  Isabel González-Alvarez; Verónica Vivancos; Carmen Coll; Bárbara Sánchez-Dengra; Elena Aznar; Alejandro Ruiz-Picazo; Marival Bermejo; Félix Sancenón; María Auxiliadora Dea-Ayuela; Marta Gonzalez-Alvarez; Ramón Martínez-Máñez
Journal:  Pharmaceutics       Date:  2021-01-13       Impact factor: 6.321

7.  Gated Organonanoclays for Large Biomolecules: Controlled Release Triggered by Surfactant Stimulus.

Authors:  Elisa Poyatos-Racionero; Édgar Pérez-Esteve; Serena Medaglia; Elena Aznar; José M Barat; Ramón Martínez-Máñez; Maria Dolores Marcos; Andrea Bernardos
Journal:  Nanomaterials (Basel)       Date:  2022-08-05       Impact factor: 5.719
  7 in total

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