Literature DB >> 2507689

The role of vitamin C in iron absorption.

L Hallberg, M Brune, L Rossander.   

Abstract

Iron requirements remain the same despite the current lower energy requirement. This means that more iron must be absorbed per unit energy. A higher bioavailability of the dietary iron can be achieved by increasing the content of food components enhancing iron absorption (ascorbic acid, meat/fish) or by decreasing the content of inhibitors (e.g., phytates, tannins). The latter is not feasible considering the recent and reasonable trend toward increasing the intake of dietary fibre. The key role of ascorbic acid for the absorption of dietary nonheme iron is generally accepted. The reasons for its action are twofold: (1) the prevention of the formation of insoluble and unabsorbable iron compounds and (2) the reduction of ferric to ferrous iron, which seems to be a requirement for the uptake of iron into the mucosal cells.

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Year:  1989        PMID: 2507689

Source DB:  PubMed          Journal:  Int J Vitam Nutr Res Suppl


  14 in total

1.  The impact of a meat- versus a vegetable-based diet on iron status in women of childbearing age with small iron stores.

Authors:  Inge Tetens; Karen M Bendtsen; Marianne Henriksen; Annette K Ersbøll; Nils Milman
Journal:  Eur J Nutr       Date:  2007-11-02       Impact factor: 5.614

2.  Hemoglobin and plasma vitamin C levels in patients on peritoneal dialysis.

Authors:  Fredric O Finkelstein; Peter Juergensen; Suxin Wang; Sally Santacroce; Mark Levine; Peter Kotanko; Nathan W Levin; Garry J Handelman
Journal:  Perit Dial Int       Date:  2010-06-17       Impact factor: 1.756

3.  Chelation of intracellular iron enhances endothelial barrier function: a role for vitamin C?

Authors:  James M May; Zhi-chao Qu
Journal:  Arch Biochem Biophys       Date:  2010-05-26       Impact factor: 4.013

4.  A Review of Nutrients and Compounds, Which Promote or Inhibit Intestinal Iron Absorption: Making a Platform for Dietary Measures That Can Reduce Iron Uptake in Patients with Genetic Haemochromatosis.

Authors:  Nils Thorm Milman
Journal:  J Nutr Metab       Date:  2020-09-14

5.  Haemodynamic instability of uncommon aetiology in Switzerland.

Authors:  Lorenzo Pucci; Orane Addor; Hervé Duplain
Journal:  BMJ Case Rep       Date:  2016-03-18

6.  Palpable purpura with an unexpected outcome.

Authors:  Anne Friesgaard Christensen; Ole Clemmensen; Peter Junker
Journal:  Case Rep Rheumatol       Date:  2013-07-15

7.  Edaphic and Phytochemical Factors as Predictors of Equine Grass Sickness Cases in the UK.

Authors:  Sarah E Edwards; Kathrin E Martz; Anja Rogge; Michael Heinrich
Journal:  Front Pharmacol       Date:  2010-10-25       Impact factor: 5.810

Review 8.  Ascorbate as a co-factor for fe- and 2-oxoglutarate dependent dioxygenases: physiological activity in tumor growth and progression.

Authors:  Caroline Kuiper; Margreet C M Vissers
Journal:  Front Oncol       Date:  2014-12-10       Impact factor: 6.244

Review 9.  Nutritional implications for ultra-endurance walking and running events.

Authors:  Eric Williamson
Journal:  Extrem Physiol Med       Date:  2016-11-21

Review 10.  Vitamin C Content in Fruits: Biosynthesis and Regulation.

Authors:  Mario Fenech; Iraida Amaya; Victoriano Valpuesta; Miguel A Botella
Journal:  Front Plant Sci       Date:  2019-01-24       Impact factor: 5.753

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