Acute tubular necrosis and dengue.

February 24th, 2014

Sir,

The recent article on “acute tubular necrosis and dengue” is very interesting[2]. REPIZO et al. concluded that “serum creatine phosphokinase should be monitored in DF patients to allow for an early diagnosis of rhabdomyolysis and the institution of renal protective measures[2]”. In fact, the renal complication of dengue is not rare and it should be kept in mind for all practitioners[5]. The renal problem in dengue can be seen in either hemorrhagic or non-hemorrhagic cases[1]. The underlying etiology of renal failure is believed to be due to the poor fluid management of the infected cases[4]. The strong clinical relationship with fatality can be seen in such cases. The immunopathology seems to have little role in induction of acute tubular necrosis[3]. The patient with a previous renal problem has a greater risk to develop renal failure. A careful follow-up of the fluid replacement therapy is the key factor for success in control and prevention of acute renal episode in dengue patients.