OBJECTIVE: We wanted to identify the presentation, diagnostic work-up and treatment outcomes of patients with sinonasal malignancy at Derriford Hospital, Plymouth, UK and compare these with the European Position Paper on Endoscopic Management of Tumours of the Nose, Paranasal Sinuses and Skull Base. MATERIALS AND METHODS: This was a retrospective audit of all patients diagnosed with sinonasal malignancy over a five-year period. The clinical records and picture archiving and communications system data of the patients were reviewed. RESULTS: Thirty patients with sinonasal malignancy were identified out of 570 head and neck cancer patients. The nasal cavity was the most common site for presentation, followed by the maxillary sinuses. Fifty per cent of patients had a squamous cell carcinoma and 27 per cent had a malignant melanoma. Half of the patients presented at stage IV of the cancer and 20 per cent at stage III. Thirty-seven per cent of patients underwent surgical management and only 20 per cent of the total patient group underwent endoscopic surgery. The mortality in our series was 30 per cent over the studied period. CONCLUSION: Late-stage presentation of sinonasal malignancy has resulted in increased patient mortality in our case series. Also, we found a high incidence of malignant melanoma with high recurrence and survival rates.
OBJECTIVE: We wanted to identify the presentation, diagnostic work-up and treatment outcomes of patients with sinonasal malignancy at Derriford Hospital, Plymouth, UK and compare these with the European Position Paper on Endoscopic Management of Tumours of the Nose, Paranasal Sinuses and Skull Base. MATERIALS AND METHODS: This was a retrospective audit of all patients diagnosed with sinonasal malignancy over a five-year period. The clinical records and picture archiving and communications system data of the patients were reviewed. RESULTS: Thirty patients with sinonasal malignancy were identified out of 570 head and neck cancerpatients. The nasal cavity was the most common site for presentation, followed by the maxillary sinuses. Fifty per cent of patients had a squamous cell carcinoma and 27 per cent had a malignant melanoma. Half of the patients presented at stage IV of the cancer and 20 per cent at stage III. Thirty-seven per cent of patients underwent surgical management and only 20 per cent of the total patient group underwent endoscopic surgery. The mortality in our series was 30 per cent over the studied period. CONCLUSION: Late-stage presentation of sinonasal malignancy has resulted in increased patient mortality in our case series. Also, we found a high incidence of malignant melanoma with high recurrence and survival rates.
Authors: Francesco Perri; Raffaele Addeo; Manuel Conson; Adriana Faiella; Giuseppina Della Vittoria Scarpati; Gabriella Torre; Angela Di Biase; Paola Romanelli; Carlo Buonerba; Giuseppe Di Lorenzo; Antonio Daponte; Francesco Caponigro; Salvatore Pisconti; Roberto Pacelli; Vincenzo Ravo; Paolo Muto; Raffaele Solla Journal: Oncol Lett Date: 2017-01-11 Impact factor: 2.967
Authors: John W Rutland; Bradley N Delman; Rebecca E Feldman; Nadejda Tsankova; Hung-Mo Lin; Francesco Padormo; Raj K Shrivastava; Priti Balchandani Journal: J Neurol Surg B Skull Base Date: 2019-11-21