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Literature DB >> 2507590

Effect of radiotherapy on oral mucosa assessed by quantitative exfoliative cytology.

Abstract

The effect of radiotherapy on normal buccal mucosa was investigated using the quantitative techniques of cytomorphology (measurement of nuclear and cytoplasmic area) and DNA cytophotometry. These techniques were applied to smears obtained before, during, and after irradiation. Nuclear area and cytoplasmic area increased and DNA values were abnormal in most cases as a result of radiotherapy, returning to within normal limits one month after treatment. This contrasts strongly with the changes seen in smears from previously irradiated uterine cervices, where changes in cytomorphology may persist for several years.

Mesh：

Substances：
DNA

Year: 1989 PMID： 2507590 PMCID： PMC501793 DOI： 10.1136/jcp.42.9.940

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

23 in total

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7 in total

1. Second malignant tumours in head and neck cancer.

Authors: G R Ogden
Journal: BMJ Date: 1991-01-26

2. Quantitative assessment of various fixatives on nuclear and cytoplasmic areas in oral cytology.

Authors: G R Ogden; M W Green; J G Cowpe
Journal: Histochem J Date: 1989-12

3. Keratin profiles of normal and malignant oral mucosa using exfoliative cytology.

Authors: G R Ogden; S McQueen; D M Chisholm; E B Lane
Journal: J Clin Pathol Date: 1993-04 Impact factor: 3.411

4. Cytological Study of Breast Carcinoma Before and After Oncotherapy with Special Reference to Morphometry and Proliferative Activity.

Authors: Sananda Koley; Srabani Chakrabarti; Swapan Pathak; Asim Kumar Manna; Siddhartha Basu
Journal: Indian J Surg Date: 2013-06-26 Impact factor: 0.656

5. Abnormal Nuclear Variations in Response to Radiotherapy- As a Tool in Treatment Planning and Assessment of Prognosis.

Authors: Kumar Satish Ravi; Manisha Naithani; Sohinder Kaur; K S Reddy; Rachna Pasi
Journal: J Clin Diagn Res Date: 2016-08-01

6. The role of tobacco as an etiological agent for oral cancer: Cytomorphometrical analysis of the buccal mucosa in tobacco users.

Authors: Megha Singh; Keya Sircar; Ankita Tandon; Aman Chowdhry; Deepika Bablani Popli
Journal: Dent Res J (Isfahan) Date: 2014-11

7. Karyoanomalic frequency assay during radiation therapy - A promising marker in the prognosis of oral and oropharyngeal carcinoma.

Authors: Kumar Satish Ravi; Pushpa N B; Sanjeev Kishore; Sohinder Kaur; Vandana Mehta; Ajay S Krishnan
Journal: J Family Med Prim Care Date: 2021-12-27

7 in total