Literature DB >> 25075625

A rare association of celiac disease and aplastic anemia: case report of a child and review of literature.

Rama Kumari Badyal1, Man Updesh Singh Sachdeva, Neelam Varma, Babu Ram Thapa.   

Abstract

An association between severe aplastic anemia and other autoimmune diseases is rare and has been described in adults for eosinophilic fasciitis, thymomas, systemic lupus erythematosus, and thyroid disorders. Herein we report a patient with celiac disease who was not strictly following a gluten-free diet and presented with progressive pallor, fever, and weakness of 1 month's duration. On investigation, he had pancytopenia, which on subsequent evaluation revealed aplastic anemia. An association between aplastic anemia and celiac disease has rarely been reported. To the best of author's knowledge, only 1 pediatric case of celiac disease associated with aplastic anemia has been published. This is the second report to suggest such an association in children.

Entities:  

Keywords:  aplastic anemia; celiac disease; child; gluten-free diet

Mesh:

Substances:

Year:  2014        PMID: 25075625     DOI: 10.2350/14-05-1489-CR.1

Source DB:  PubMed          Journal:  Pediatr Dev Pathol        ISSN: 1093-5266


  4 in total

1.  Generalized Morphea Coincident With Aplastic Anemia: A Case Report.

Authors:  Madhusudan R Tapdia; T T Favas; Vijaya Nath Mishra; Abhishek Pathak; Varun K Singh
Journal:  Cureus       Date:  2022-01-05

Review 2.  Celiac disease associated with aplastic anemia in a 6-year-old girl: a case report and review of the literature.

Authors:  Omar Irfan; Sana Mahmood; Heera Nand; Gaffar Billoo
Journal:  J Med Case Rep       Date:  2018-01-23

Review 3.  Multifactorial Etiology of Anemia in Celiac Disease and Effect of Gluten-Free Diet: A Comprehensive Review.

Authors:  Rafael Martín-Masot; Maria Teresa Nestares; Javier Diaz-Castro; Inmaculada López-Aliaga; Maria Jose Muñoz Alférez; Jorge Moreno-Fernandez; José Maldonado
Journal:  Nutrients       Date:  2019-10-23       Impact factor: 5.717

4.  Atypical hematological manifestation of celiac disease: A case report of aplastic anemia in a 2-year-old child and review of the literature.

Authors:  Thea von Graffenried; Mattia Rizzi; Michel Russo; Andreas Nydegger; Simon Kayemba-Kay's
Journal:  Pediatr Investig       Date:  2021-06-18
  4 in total

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