Literature DB >> 25075553

Substituent-enabled oxidative dehydrogenative cross-coupling of 1,4-naphthoquinones with alkenes.

Chi Zhang1, Meining Wang, Zhoulong Fan, Li-Ping Sun, Ao Zhang.   

Abstract

A Rh-catalyzed oxidative dehydrogenative cross-coupling of 1,4-naphthquinones with alkenes was achieved by using a substituent-enabled C(sp(2))-H functionalization (SEF) strategy. The method shows high functional group tolerance, broad substrate scope, and great potential for further functional transformations.

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Year:  2014        PMID： 25075553     DOI： 10.1021/jo501419s

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  2 in total

1.  Metal-Free Direct Amidation of Naphthoquinones Using Hydroxamic Acids as an Amide Source: Application in the Synthesis of an HDAC6 Inhibitor.

Authors:  Cheng Zhang; C James Chou
Journal:  Org Lett       Date:  2016-10-19       Impact factor: 6.005

2.  Overcoming naphthoquinone deactivation: rhodium-catalyzed C-5 selective C-H iodination as a gateway to functionalized derivatives.

Authors:  Guilherme A M Jardim; Eufrânio N da Silva Júnior; John F Bower
Journal:  Chem Sci       Date:  2016-03-02       Impact factor: 9.825
  2 in total

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