Literature DB >> 25073688

Glutamate metabolism in major depressive disorder.

Chadi G Abdallah1, Lihong Jiang, Henk M De Feyter, Madonna Fasula, John H Krystal, Douglas L Rothman, Graeme F Mason, Gerard Sanacora.   

Abstract

Research on novel treatments for major depressive disorder focuses quite deeply on glutamate function, and this research would benefit from a brain-imaging technique that precisely quantified glutamate function. Signs of a specific form of glutamate-related dysfunction that could be targeted by novel therapies were found using novel, state-of-the-art techniques to address this issue.

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Year:  2014        PMID： 25073688      PMCID： PMC4472484          DOI： 10.1176/appi.ajp.2014.14010067

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN： 0002-953X            Impact factor:   18.112


  40 in total

1.  ¹H-[¹³C]-nuclear magnetic resonance spectroscopy measures of ketamine's effect on amino acid neurotransmitter metabolism.

Authors:  Golam M I Chowdhury; Kevin L Behar; William Cho; Monique A Thomas; Douglas L Rothman; Gerard Sanacora
Journal:  Biol Psychiatry       Date:  2011-12-09       Impact factor: 13.382

2.  Repeated stress causes cognitive impairment by suppressing glutamate receptor expression and function in prefrontal cortex.

Authors:  Eunice Y Yuen; Jing Wei; Wenhua Liu; Ping Zhong; Xiangning Li; Zhen Yan
Journal:  Neuron       Date:  2012-03-08       Impact factor: 17.173

3.  Increased ventricular lactate in chronic fatigue syndrome. III. Relationships to cortical glutathione and clinical symptoms implicate oxidative stress in disorder pathophysiology.

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Journal:  NMR Biomed       Date:  2012-01-27       Impact factor: 4.044

Review 4.  Region and state specific glutamate downregulation in major depressive disorder: a meta-analysis of (1)H-MRS findings.

Authors:  J J Luykx; K G Laban; M P van den Heuvel; M P M Boks; R C W Mandl; R S Kahn; S C Bakker
Journal:  Neurosci Biobehav Rev       Date:  2011-06-06       Impact factor: 8.989

Review 5.  The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission.

Authors:  Maurizio Popoli; Zhen Yan; Bruce S McEwen; Gerard Sanacora
Journal:  Nat Rev Neurosci       Date:  2011-11-30       Impact factor: 34.870

Review 6.  Impaired mitochondrial function in psychiatric disorders.

Authors:  Husseini Manji; Tadafumi Kato; Nicholas A Di Prospero; Seth Ness; M Flint Beal; Michael Krams; Guang Chen
Journal:  Nat Rev Neurosci       Date:  2012-04-18       Impact factor: 34.870

7.  Cortical energy demands of signaling and nonsignaling components in brain are conserved across mammalian species and activity levels.

Authors:  Fahmeed Hyder; Douglas L Rothman; Maxwell R Bennett
Journal:  Proc Natl Acad Sci U S A       Date:  2013-01-14       Impact factor: 11.205

8.  Marked reductions in visual evoked responses but not γ-aminobutyric acid concentrations or γ-band measures in remitted depression.

Authors:  Alexander Shaw; Jennifer Brealy; Heather Richardson; Suresh D Muthukumaraswamy; Richard A Edden; C John Evans; Nicolaas A J Puts; Krishna D Singh; Paul A Keedwell
Journal:  Biol Psychiatry       Date:  2012-11-28       Impact factor: 13.382

9.  Potential of pretreatment neural activity in the visual cortex during emotional processing to predict treatment response to scopolamine in major depressive disorder.

Authors:  Maura L Furey; Wayne C Drevets; Elana M Hoffman; Erica Frankel; Andrew M Speer; Carlos A Zarate
Journal:  JAMA Psychiatry       Date:  2013-03       Impact factor: 21.596

Review 10.  Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond.

Authors:  John H Krystal; Gerard Sanacora; Ronald S Duman
Journal:  Biol Psychiatry       Date:  2013-06-15       Impact factor: 13.382
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  49 in total

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Journal:  J Neurosci       Date:  2019-02-25       Impact factor: 6.167

2.  Longer-term open-label study of adjunctive riluzole in treatment-resistant depression.

Authors:  Hitoshi Sakurai; Christina Dording; Albert Yeung; Simmie Foster; Felipe Jain; Trina Chang; Nhi-Ha Trinh; Richard Bernard; Sean Boyden; Syed Z Iqbal; Samuel T Wilkinson; Sanjay J Mathew; David Mischoulon; Maurizio Fava; Cristina Cusin
Journal:  J Affect Disord       Date:  2019-07-02       Impact factor: 4.839

Review 3.  Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments.

Authors:  Ronald S Duman; Gerard Sanacora; John H Krystal
Journal:  Neuron       Date:  2019-04-03       Impact factor: 17.173

4.  The Nucleus Accumbens and Ketamine Treatment in Major Depressive Disorder.

Authors:  Chadi G Abdallah; Andrea Jackowski; Ramiro Salas; Swapnil Gupta; João R Sato; Xiangling Mao; Jeremy D Coplan; Dikoma C Shungu; Sanjay J Mathew
Journal:  Neuropsychopharmacology       Date:  2017-03-08       Impact factor: 7.853

Review 5.  Increasing Nrf2 Activity as a Treatment Approach in Neuropsychiatry.

Authors:  G Morris; A J Walker; K Walder; M Berk; W Marx; A F Carvalho; M Maes; B K Puri
Journal:  Mol Neurobiol       Date:  2021-01-07       Impact factor: 5.590

6.  Ketamine Treatment and Global Brain Connectivity in Major Depression.

Authors:  Chadi G Abdallah; Lynnette A Averill; Katherine A Collins; Paul Geha; Jaclyn Schwartz; Christopher Averill; Kaitlin E DeWilde; Edmund Wong; Alan Anticevic; Cheuk Y Tang; Dan V Iosifescu; Dennis S Charney; James W Murrough
Journal:  Neuropsychopharmacology       Date:  2016-09-08       Impact factor: 7.853

7.  Prophylactic ketamine alters nucleotide and neurotransmitter metabolism in brain and plasma following stress.

Authors:  Josephine C McGowan; Collin Hill; Alessia Mastrodonato; Christina T LaGamma; Alexander Kitayev; Rebecca A Brachman; Niven R Narain; Michael A Kiebish; Christine A Denny
Journal:  Neuropsychopharmacology       Date:  2018-03-29       Impact factor: 7.853

8.  Meta-analysis of central and peripheral γ-aminobutyric acid levels in patients with unipolar and bipolar depression.

Authors:  Bruno Romeo; Walid Choucha; Philippe Fossati; Jean-Yves Rotge
Journal:  J Psychiatry Neurosci       Date:  2017-10-02       Impact factor: 6.186

Review 9.  Glutamate and Gamma-Aminobutyric Acid Systems in the Pathophysiology of Major Depression and Antidepressant Response to Ketamine.

Authors:  Marc S Lener; Mark J Niciu; Elizabeth D Ballard; Minkyung Park; Lawrence T Park; Allison C Nugent; Carlos A Zarate
Journal:  Biol Psychiatry       Date:  2016-05-12       Impact factor: 13.382

10.  Online Effects of Transcranial Direct Current Stimulation in Real Time on Human Prefrontal and Striatal Metabolites.

Authors:  Antoine Hone-Blanchet; Richard A Edden; Shirley Fecteau
Journal:  Biol Psychiatry       Date:  2015-12-01       Impact factor: 13.382
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