Literature DB >> 25073599

Identification and replication of a combined epigenetic and genetic biomarker predicting suicide and suicidal behaviors.

Jerry Guintivano1, Tori Brown, Alison Newcomer, Marcus Jones, Olivia Cox, Brion S Maher, William W Eaton, Jennifer L Payne, Holly C Wilcox, Zachary A Kaminsky.   

Abstract

Considerable research suggests that suicide involves effects of genes, the environment, and their interaction. Analysis of three independent data sets of post-mortem brains revealed signs of increased methylation in one particular gene, SKA2, a finding that was extended to peripheral blood samples from other cohorts of prospectively followed individuals.

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Year:  2014        PMID： 25073599      PMCID： PMC7081376          DOI： 10.1176/appi.ajp.2014.14010008

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN： 0002-953X            Impact factor:   18.112


  38 in total

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  50 in total

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6.  Traumatic Stress Interacts With Bipolar Disorder Genetic Risk to Increase Risk for Suicide Attempts.

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7.  Descriptive epidemiology of suicide attempts and suicide in the remote villages of French Guiana.

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8.  The Role of Epigenetic Dysregulation in Suicidal Behaviors.

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9.  Epigenome-wide association of PTSD from heterogeneous cohorts with a common multi-site analysis pipeline.

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10.  Genomewide association studies of suicide attempts in US soldiers.

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