Literature DB >> 25071972

Multi-modal label-free imaging based on a femtosecond fiber laser.

Ruxin Xie1, Jue Su1, Eric C Rentchler2, Ziyan Zhang3, Carey K Johnson2, Honglian Shi3, Rongqing Hui1.   

Abstract

We demonstrate multi-mode microscopy based on a single femtosecond fiber laser. Coherent anti-Stokes Raman scattering (CARS), stimulated Raman scattering (SRS) and photothermal images can be obtained simultaneously with this simplified setup. Distributions of lipid and hemoglobin in sliced mouse brain samples and blood cells are imaged. The dependency of signal amplitude on the pump power and pump modulation frequency is characterized, which allows to isolate the impact from different contributions.

Entities:  

Keywords:  (060.5295) Photonic crystal fibers; (140.3510) Lasers, fiber; (170.3880) Medical and biological imaging; (180.4315) Nonlinear microscopy; (300.6230) Spectroscopy, coherent anti-Stokes Raman scattering; (300.6430) Spectroscopy, photothermal; (300.6450) Spectroscopy, Raman

Year:  2014        PMID： 25071972      PMCID： PMC4102372          DOI： 10.1364/BOE.5.002390

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN： 2156-7085            Impact factor:   3.732


  26 in total

1.  Determination of subyoctomole amounts of nonfluorescent molecules using a thermal lens microscope: subsingle-molecule determination.

Authors:  M Tokeshi; M Uchida; A Hibara; T Sawada; T Kitamori
Journal:  Anal Chem       Date:  2001-05-01       Impact factor: 6.986

2.  Large two-photon absorptivity of hemoglobin in the infrared range of 780-880 nm.

Authors:  G Omar Clay; Chris B Schaffer; David Kleinfeld
Journal:  J Chem Phys       Date:  2007-01-14       Impact factor: 3.488

3.  Fiber optical parametric oscillator for coherent anti-Stokes Raman scattering microscopy.

Authors:  Erin S Lamb; Simon Lefrancois; Minbiao Ji; William J Wadsworth; X Sunney Xie; Frank W Wise
Journal:  Opt Lett       Date:  2013-10-15       Impact factor: 3.776

4.  Fiber-format stimulated-Raman-scattering microscopy from a single laser oscillator.

Authors:  Alessio Gambetta; Vikas Kumar; Giulia Grancini; Dario Polli; Roberta Ramponi; Giulio Cerullo; Marco Marangoni
Journal:  Opt Lett       Date:  2010-01-15       Impact factor: 3.776

5.  Two-photon microscopy with wavelength switchable fiber laser excitation.

Authors:  Jay R Unruh; E S Price; Roque G Molla; Lisa Stehno-Bittel; Carey K Johnson; Rongqing Hui
Journal:  Opt Express       Date:  2006-10-16       Impact factor: 3.894

6.  Multimodal coherent anti-Stokes Raman spectroscopic imaging with a fiber optical parametric oscillator.

Authors:  Yan-Hua Zhai; Christiane Goulart; Jay E Sharping; Huifeng Wei; Su Chen; Weijun Tong; Mikhail N Slipchenko; Delong Zhang; Ji-Xin Cheng
Journal:  Appl Phys Lett       Date:  2011-05-10       Impact factor: 3.791

7.  All-fiber CARS microscopy of live cells.

Authors:  Adrian F Pegoraro; Andrew Ridsdale; Douglas J Moffatt; John Paul Pezacki; Brian K Thomas; Libin Fu; Liang Dong; Martin E Fermann; Albert Stolow
Journal:  Opt Express       Date:  2009-11-09       Impact factor: 3.894

8.  Stimulated Raman Scattering Microscopy with a Robust Fibre Laser Source.

Authors:  Christian W Freudiger; Wenlong Yang; Gary R Holtom; Nasser Peyghambarian; X Sunney Xie; Khanh Q Kieu
Journal:  Nat Photonics       Date:  2014-02-01       Impact factor: 38.771

9.  Single fiber laser based wavelength tunable excitation for CRS spectroscopy.

Authors:  Jue Su; Ruxin Xie; Carey K Johnson; Rongqing Hui
Journal:  J Opt Soc Am B       Date:  2013-06-01       Impact factor: 2.106

10.  Coherent anti-Stokes Raman scattering hyperspectral tissue imaging with a wavelength-swept system.

Authors:  Steve Bégin; Bryan Burgoyne; Vincent Mercier; Alain Villeneuve; Réal Vallée; Daniel Côté
Journal:  Biomed Opt Express       Date:  2011-04-22       Impact factor: 3.732
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  4 in total

1.  Multimodal fiber source for nonlinear microscopy based on a dissipative soliton laser.

Authors:  Erin S Lamb; Frank W Wise
Journal:  Biomed Opt Express       Date:  2015-08-06       Impact factor: 3.732

2.  Two-frequency CARS imaging by switching fiber laser excitation.

Authors:  Eric C Rentchler; Ruxin Xie; Rongqing Hui; Carey K Johnson
Journal:  Microsc Res Tech       Date:  2018-01-11       Impact factor: 2.769

3.  Evans blue dye-enhanced imaging of the brain microvessels using spectral focusing coherent anti-Stokes Raman scattering microscopy.

Authors:  Bo-Ram Lee; Kyung-Il Joo; Eun Sook Choi; Junghoon Jahng; Hyunmin Kim; Eunjoo Kim
Journal:  PLoS One       Date:  2017-10-19       Impact factor: 3.240

4.  High-contrast, fast chemical imaging by coherent Raman scattering using a self-synchronized two-colour fibre laser.

Authors:  Cihang Kong; Christian Pilger; Henning Hachmeister; Xiaoming Wei; Tom H Cheung; Cora S W Lai; Nikki P Lee; Kevin K Tsia; Kenneth K Y Wong; Thomas Huser
Journal:  Light Sci Appl       Date:  2020-02-24       Impact factor: 17.782
  4 in total

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