Literature DB >> 25068416

Diastereoselective synthesis of fused lactone-pyrrolidinones; application to a formal synthesis of (-)-salinosporamide A.

Angus W J Logan1, Simon J Sprague, Robert W Foster, Léo B Marx, Vincenzo Garzya, Michal S Hallside, Amber L Thompson, Jonathan W Burton.   

Abstract

A mild, diastereoselective synthesis of fused lactone-pyrrolidinones using an oxidative radical cyclization is reported. The methodology is demonstrated in a formal synthesis of (-)-salinosporamide A.

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Year:  2014        PMID： 25068416     DOI： 10.1021/ol501662t

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Total Synthesis of (-)-Salinosporamide A via a Late Stage C-H Insertion.

Authors:  Hadi Gholami; Aman Kulshrestha; Olivia K Favor; Richard J Staples; Babak Borhan
Journal:  Angew Chem Int Ed Engl       Date:  2019-04-10       Impact factor: 15.336

2.  Stereocontrolled access to δ-lactone-fused-γ-lactams bearing angular benzylic quaternary stereocenters.

Authors:  Timothy K Beng; Morgan J Rodriguez; Claire Borg
Journal:  RSC Adv       Date:  2022-06-14       Impact factor: 4.036

3.  A Short Synthesis of Aphanamol I in Both Racemic and Enantiopure Forms.

Authors:  Steven J Ferrara; Jonathan W Burton
Journal:  Chemistry       Date:  2016-07-08       Impact factor: 5.236

Review 4.  Marine Rare Actinobacteria: Isolation, Characterization, and Strategies for Harnessing Bioactive Compounds.

Authors:  Dipesh Dhakal; Anaya Raj Pokhrel; Biplav Shrestha; Jae Kyung Sohng
Journal:  Front Microbiol       Date:  2017-06-15       Impact factor: 5.640
  4 in total

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