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Literature DB >> 25067941

Biological activities of 'noninfectious' influenza A virus particles.

Abstract

Only a small fraction of influenza A virus (IAV) particles within a viral population register as infectious by traditional infectivity assays. Despite constituting the most abundant product of influenza infection, the role that the 'noninfectious' particle fraction plays in the biology of the virus has largely been ignored. This review shines a light on this oft-ignored population by highlighting studies, both old and new, that describe the unique biological activities of these particles, and discussing what this population can tell us about the biology of IAV evolution and disease.

Entities: Chemical Disease Gene Species

Keywords: DI particles; aggregation; genome packaging; heterogeneity; influenza; noninfectious; semi-infectious; virion; virus

Year: 2014 PMID： 25067941 PMCID： PMC4109409 DOI： 10.2217/fvl.13.118

Source DB: PubMed Journal: Future Virol ISSN： 1746-0794 Impact factor: 1.831

99 in total

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Authors: Jeremy S Rossman; George P Leser; Robert A Lamb
Journal: J Virol Date: 2012-08-08 Impact factor: 5.103

2. An amino acid change in the non-structural NS2 protein of an influenza A virus mutant is responsible for the generation of defective interfering (DI) particles by amplifying DI RNAs and suppressing complementary RNA synthesis.

Authors: T Odagiri; K Tominaga; K Tobita; S Ohta
Journal: J Gen Virol Date: 1994-01 Impact factor: 3.891

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Authors: R K Akkina; T M Chambers; D P Nayak
Journal: J Virol Date: 1984-08 Impact factor: 5.103

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Authors: P Suárez; J Valcárcel; J Ortín
Journal: J Virol Date: 1992-04 Impact factor: 5.103

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Authors: P A Jennings; J T Finch; G Winter; J S Robertson
Journal: Cell Date: 1983-09 Impact factor: 41.582

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Authors: E N Kantorovich-Prokudina; N P Semyonova; O N Berezina; V M Zhdanov
Journal: J Gen Virol Date: 1980-09 Impact factor: 3.891

7. Reassortment complements spontaneous mutation in influenza A virus NP and M1 genes to accelerate adaptation to a new host.

Authors: William L Ince; Aissatou Gueye-Mbaye; Jack R Bennink; Jonathan W Yewdell
Journal: J Virol Date: 2013-01-30 Impact factor: 5.103

8. H5N1 hybrid viruses bearing 2009/H1N1 virus genes transmit in guinea pigs by respiratory droplet.

Authors: Ying Zhang; Qianyi Zhang; Huihui Kong; Yongping Jiang; Yuwei Gao; Guohua Deng; Jianzhong Shi; Guobin Tian; Liling Liu; Jinxiong Liu; Yuntao Guan; Zhigao Bu; Hualan Chen
Journal: Science Date: 2013-05-02 Impact factor: 47.728

9. Aerosol transmission is an important mode of influenza A virus spread.

Authors: Benjamin J Cowling; Dennis K M Ip; Vicky J Fang; Piyarat Suntarattiwong; Sonja J Olsen; Jens Levy; Timothy M Uyeki; Gabriel M Leung; J S Malik Peiris; Tawee Chotpitayasunondh; Hiroshi Nishiura; James Mark Simmerman
Journal: Nat Commun Date: 2013 Impact factor: 14.919

10. Cryotomography of budding influenza A virus reveals filaments with diverse morphologies that mostly do not bear a genome at their distal end.

Authors: Swetha Vijayakrishnan; Colin Loney; David Jackson; Worawit Suphamungmee; Frazer J Rixon; David Bhella
Journal: PLoS Pathog Date: 2013-06-06 Impact factor: 6.823

33 in total

1. Computational and molecular analysis of conserved influenza A virus RNA secondary structures involved in infectious virion production.

Authors: Yuki Kobayashi; Bernadeta Dadonaite; Neeltje van Doremalen; Yoshiyuki Suzuki; Wendy S Barclay; Oliver G Pybus
Journal: RNA Biol Date: 2016-07-11 Impact factor: 4.652

2. Amphipathic Helices of Cellular Proteins Can Replace the Helix in M2 of Influenza A Virus with Only Small Effects on Virus Replication.

Authors: Bodan Hu; Stefanie Siche; Lars Möller; Michael Veit
Journal: J Virol Date: 2020-01-17 Impact factor: 5.103

3. Influenza A virus nucleoprotein selectively decreases neuraminidase gene-segment packaging while enhancing viral fitness and transmissibility.

Authors: Christopher B Brooke; William L Ince; Jiajie Wei; Jack R Bennink; Jonathan W Yewdell
Journal: Proc Natl Acad Sci U S A Date: 2014-11-10 Impact factor: 11.205

4. Dissecting the Components of Sindbis Virus from Arthropod and Vertebrate Hosts: Implications for Infectivity Differences.

Authors: Carmen A Dunbar; Vamseedhar Rayaprolu; Joseph C-Y Wang; Christopher J Brown; Emma Leishman; Sara Jones-Burrage; Jonathan C Trinidad; Heather B Bradshaw; David E Clemmer; Suchetana Mukhopadhyay; Martin F Jarrold
Journal: ACS Infect Dis Date: 2019-04-15 Impact factor: 5.084