Literature DB >> 2506784

Evaluation of the upper airway by computerized tomography in patients undergoing uvulopalatopharyngoplasty for obstructive sleep apnea.

J W Shepard1, S E Thawley.   

Abstract

This study utilized computerized tomography (CT) to evaluate the effects of uvulopalatopharyngoplasty (UPPP) on upper airway (UA) dimensions. The objectives were to determine whether CT scan results would be useful in identifying UA characteristics predictive of a good surgical result as well as elucidating reasons for failure of this operative procedure. Twenty-three male patients with obstructive sleep apnea (OSA) had CT scans and polysomnography performed before and after UPPP. Preoperatively, the apnea plus hypopnea index (AHI) was 64 +/- 6 per hour and the minimal UA cross-sectional area (Amin) was located at 10 and 20 mm below the level of the hard palate in 87% (20 of 23) of the patients. Uvulopalatopharyngoplasty more than doubled UA cross-sectional areas at these two proximal levels. In contrast, the hypopharyngeal segment located 50 to 70 mm below the hard palate decreased in cross-sectional area by 23 to 25% after surgery. Eight patients (35%) had a good response to UPPP based on a greater than 50% decrease in AHI. Preoperatively, seven of these eight patients had Amin located 20 mm below the hard palate. Uvulopalatopharyngoplasty increased Amin and oropharyngeal cross-sectional areas to a greater extent in the good than in the poor responders. A poor response to UPPP was associated with preoperative Amin greater than 1 cm2, location at site other than 20 mm below the hard palate, and postoperative narrowing at the level of the hard palate. Patients with Amin less than 1.0 cm2 located 20 mm below the hard palate (lower velopharynx) were most likely to obtain a favorable result with surgery.

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Year:  1989        PMID: 2506784     DOI: 10.1164/ajrccm/140.3.711

Source DB:  PubMed          Journal:  Am Rev Respir Dis        ISSN: 0003-0805


  16 in total

1.  Effect of reduced expiratory pressure on pharyngeal size during nasal positive airway pressure in patients with sleep apnoea: evaluation by continuous computed tomography.

Authors:  M Gugger; P Vock
Journal:  Thorax       Date:  1992-10       Impact factor: 9.139

2.  Evaluation of airway obstruction at soft palate level in male patients with obstructive sleep apnea/hypopnea syndrome: dynamic 3-dimensional CT imaging of upper airway.

Authors:  Ying Xiao; Xiong Chen; Heshui Shi; Yang Yang; Liechun He; Jiaqi Dong; Weijia Kong
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2011-06-14

Review 3.  Sleep x 9: an approach to treatment of obstructive sleep apnoea/hypopnoea syndrome including upper airway surgery.

Authors:  C F Ryan
Journal:  Thorax       Date:  2005-07       Impact factor: 9.139

4.  [Sleep-related breathing disorders. Sleep anamnesis questionnaire and determination of clinical results within the framework of staged diagnostics].

Authors:  Y Fischer; A Neagos; W Pirsig
Journal:  HNO       Date:  2005-11       Impact factor: 1.284

Review 5.  Obstructive sleep apnoea.

Authors:  S G McNamara; R R Grunstein; C E Sullivan
Journal:  Thorax       Date:  1993-07       Impact factor: 9.139

Review 6.  Mechanisms of sleep-disordered breathing: causes and consequences.

Authors:  Richard S T Leung; Vikram R Comondore; Clodagh M Ryan; Daniel Stevens
Journal:  Pflugers Arch       Date:  2011-11-15       Impact factor: 3.657

7.  Upper airway obstructive disease in mucopolysaccharidoses: polysomnography, computed tomography and nasal endoscopy findings.

Authors:  F Santamaria; M V Andreucci; G Parenti; M Polverino; D Viggiano; S Montella; A Cesaro; R Ciccarelli; B Capaldo; G Andria
Journal:  J Inherit Metab Dis       Date:  2007-06-14       Impact factor: 4.982

Review 8.  Flow-regulatory function of upper airway in health and disease: a unified pathogenetic view of sleep-disordered breathing.

Authors:  S S Park
Journal:  Lung       Date:  1993       Impact factor: 2.584

9.  Associated predictors of therapeutic response to uvulopharyngopalatoplasty for severe obstructive sleep apnea hypopnea syndrome.

Authors:  Su Ru Liu; Hong Liang Yi; Shan Kai Yin; Jian Guan; Bin Chen; Li Li Meng; Kai Ming Su
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-02-27       Impact factor: 2.503

10.  Somnofluoroscopy, computed tomography, and cephalometry in the assessment of the airway in obstructive sleep apnoea.

Authors:  J L Pepin; G Ferretti; D Veale; P Romand; M Coulomb; C Brambilla; P A Lévy
Journal:  Thorax       Date:  1992-03       Impact factor: 9.139

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