Literature DB >> 2506428

A locus involved in kanamycin, chloramphenicol and L-serine resistance is located in the bglY-galU region of the Escherichia coli K12 chromosome.

P Lejeune1, P Bertin, C Walon, K Willemot, C Colson, A Danchin.   

Abstract

Spontaneous mutants of Escherichia coli K12 displaying an increased level of the kanamycin resistance conferred by plasmid pGR71 were selected. Several mutants obtained in this way apparently carry large chromosomal deletions extending into galU and/or bglY (27 min). This positive selection of deletions allowed detection of a new locus located between galU and bglY. Deletions of this locus are responsible for increased resistance to kanamycin (Irk), decreased resistance to L-serine in minimal medium (Drs) and decreased resistance to chloramphenicol (Drc) when a cat gene is present in the bacteria.

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Year:  1989        PMID： 2506428     DOI： 10.1007/bf00331292

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN： 0026-8925


  11 in total

1.  Chloramphenicol acetyltransferase from chloramphenicol-resistant bacteria.

Authors:  W V Shaw
Journal:  Methods Enzymol       Date:  1975       Impact factor: 1.600

2.  MUTATIONS IN ESCHERICHIA COLI THAT AFFECT URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHORYLASE ACTIVITY AND GALACTOSE FERMENTATION.

Authors:  T FUKASAWA; K JOKURA; K KURAHASHI
Journal:  Biochim Biophys Acta       Date:  1963-09-10

3.  Biochemical observations on E. coli mutants defective in uridine diphosphoglucose.

Authors:  T A SUNDARARAJAN; A M RAPIN; H M KALCKAR
Journal:  Proc Natl Acad Sci U S A       Date:  1962-12-15       Impact factor: 11.205

4.  A rapid test for the rel A mutation in E. coli.

Authors:  M Uzan; A Danchin
Journal:  Biochem Biophys Res Commun       Date:  1976-04-05       Impact factor: 3.575

5.  Correlation between the serine sensitivity and the derepressibility of the ilv genes in Escherichia coli relA- mutants.

Authors:  M Uzan; A Danchin
Journal:  Mol Gen Genet       Date:  1978-09-20

6.  A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli.

Authors:  C F Higgins; C J Dorman; D A Stirling; L Waddell; I R Booth; G May; E Bremer
Journal:  Cell       Date:  1988-02-26       Impact factor: 41.582

7.  Expression of Tn9-derived chloramphenicol resistance in Bacillus subtilis.

Authors:  D S Goldfarb; R H Doi; R L Rodriguez
Journal:  Nature       Date:  1981-09-24       Impact factor: 49.962

8.  Construction of broad-host-range cosmid cloning vectors: identification of genes necessary for growth of Methylobacterium organophilum on methanol.

Authors:  L N Allen; R S Hanson
Journal:  J Bacteriol       Date:  1985-03       Impact factor: 3.490

9.  The use of suicide substrates to select mutants of Escherichia coli lacking enzymes of alcohol fermentation.

Authors:  P R Cunningham; D P Clark
Journal:  Mol Gen Genet       Date:  1986-12

10.  Cryptic operon for beta-glucoside metabolism in Escherichia coli K12: genetic evidence for a regulatory protein.

Authors:  R Defez; M De Felice
Journal:  Genetics       Date:  1981-01       Impact factor: 4.562
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  9 in total

1.  Isolation and characterization of Escherichia coli mutants blocked in production of membrane-derived oligosaccharides.

Authors:  A C Weissborn; M K Rumley; E P Kennedy
Journal:  J Bacteriol       Date:  1992-07       Impact factor: 3.490

2.  Mutations in bglY, the structural gene for the DNA-binding protein H1 of Escherichia coli, increase the expression of the kanamycin resistance gene carried by plasmid pGR71.

Authors:  P Bertin; P Lejeune; C Colson; A Danchin
Journal:  Mol Gen Genet       Date:  1992-05

3.  Functional replacement of the oligomerization domain of H-NS by the Hha protein of Escherichia coli.

Authors:  Sonia Rodríguez; José María Nieto; Cristina Madrid; Antonio Juárez
Journal:  J Bacteriol       Date:  2005-08       Impact factor: 3.490

4.  Mutations in the bglY gene increase the frequency of spontaneous deletions in Escherichia coli K-12.

Authors:  P Lejeune; A Danchin
Journal:  Proc Natl Acad Sci U S A       Date:  1990-01       Impact factor: 11.205

5.  Locations of genes in the nar-adhE region of the Escherichia coli K-12 chromosome.

Authors:  M R Leonardo; D P Clark
Journal:  J Bacteriol       Date:  1991-03       Impact factor: 3.490

Review 6.  Linkage map of Escherichia coli K-12, edition 10: the traditional map.

Authors:  M K Berlyn
Journal:  Microbiol Mol Biol Rev       Date:  1998-09       Impact factor: 11.056

7.  The H-NS protein modulates the activation of the ilvIH operon of Escherichia coli K12 by Lrp, the leucine regulatory protein.

Authors:  M Levinthal; P Lejeune; A Danchin
Journal:  Mol Gen Genet       Date:  1994-03

8.  Organization and functions of genes in the upstream region of tyrT of Escherichia coli: phenotypes of mutants with partial deletion of a new gene (tgs).

Authors:  M Bösl; H Kersten
Journal:  J Bacteriol       Date:  1994-01       Impact factor: 3.490

9.  The H-NS protein is involved in the biogenesis of flagella in Escherichia coli.

Authors:  P Bertin; E Terao; E H Lee; P Lejeune; C Colson; A Danchin; E Collatz
Journal:  J Bacteriol       Date:  1994-09       Impact factor: 3.490
  9 in total

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