| Literature DB >> 25064215 |
Juan Liu1, Cheng Peng2, Cheng-Jun He1, Jian-Lin Liu3, Ya-Cong He1, Li Guo1, Qin-Mei Zhou1, Huai Yang1, Liang Xiong4.
Abstract
Five new amino γ-butenolides, fritenolide A (1), B (2), C (3), D (4), and E (5), along with four known compounds, were isolated from the bulbs of Fritillaria unibracteata. Their structures were determined by spectroscopic analysis, including 1D NMR, 2D NMR, HRESIMS, HRESIMS/MS, IR, and CD techniques. All isolates were evaluated for the protective activity on injured hepatocytes and cytotoxic activity on human cancer cells in vitro. The unusual amino butenolides were isolated from the Liliaceae family for the first time.Entities:
Keywords: Amide alkaloids; Amino butenolides; Fritillaria unibracteata; Liliaceae
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Year: 2014 PMID： 25064215 DOI： 10.1016/j.fitote.2014.07.009
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882