| Literature DB >> 2506350 |
A P Johnson1, M Tuffrey, D Taylor-Robinson.
Abstract
Five strains of mice (C3H, CBA, BALB/c, TO and ICR) were inoculated intra-vaginally with Neisseria gonorrhoeae in an attempt to produce an animal model of gonorrhoea. Of a total of 68 mice inoculated, only three (4.4%) were culture-positive after 3 days. Histological examination of both the genital mucosa of inoculated animals, and the mucosa of genital tract organ cultures inoculated in vitro failed to show any evidence of gonococcal adherence or colonisation. Mice of these strains, therefore, appear resistant to gonococcal infection of the genital tract.Entities:
Mesh：
Year: 1989 PMID： 2506350 DOI： 10.1099/00222615-30-1-33
Source DB: PubMed Journal: J Med Microbiol ISSN： 0022-2615 Impact factor: 2.472