| Literature DB >> 2506346 |
C Johnston1, L Webb, J Daley, G S Spathis.
Abstract
Three cases are presented which emphasize the importance of hyponatraemia as a cause of grand mal seizures. The combination of hydrochlorothiazide and amiloride appears to increase the risk of hyponatraemia. We discuss the aetiology and treatment of hyponatraemia and review the necessity for such combination therapy. We recommend caution in prescribing diuretics and preparations such as Moduretic should be used only in those few patients shown to need potassium supplementation.Entities:
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Year: 1989 PMID: 2506346 PMCID: PMC1292254 DOI: 10.1177/014107688908200811
Source DB: PubMed Journal: J R Soc Med ISSN: 0141-0768 Impact factor: 18.000