Literature DB >> 25062602

Health outcomes of delayed union and nonunion of femoral and tibial shaft fractures.

Wei-Han Tay1, Richard de Steiger2, Martin Richardson2, Russell Gruen3, Zsolt J Balogh4.   

Abstract

INTRODUCTION: Knowledge about the functional consequences of lower limb long bone fractures is helpful to inform patients, clinicians and employers about their recovery process and prognosis. This study aims to describe the epidemiology and health outcomes of femoral and tibial shaft fractures treated at two level I trauma centres, by comparing the differences between patients with delayed union or nonunion and patients with union. PATIENTS AND METHODS: An analysis of registry data over two years, supplemented with medical record review, was conducted. Fracture healing was retrospectively assessed by clinical and radiological evidence of union, and the need for surgical intervention. SF-12 scores, and work and pain status were prospectively recorded at six and twelve months post injury.
RESULTS: 285 fractures progressed to union and 138 fractures developed delayed union or nonunion. There was a significant difference between the two cohorts with regards to the mechanism of injury, association with multi-trauma, open fractures, grade of Gustilo classification, patient fund source, smoking status and presence of comorbidities. The SF-12 physical component score was less than 50 at both six and twelve months with improvement in the union group, but not in the delayed union or nonunion group. 72% of patients with union had returned to work at one year, but 54% continued to have pain. The difference compared to patients with delayed union or nonunion was significant. DISCUSSION: Even patients whose fractures unite in the expectant time-frame will have residual physical disability. Patients with delayed union or nonunion have still poorer outcomes, including ongoing problems with returning to work and pain. It is important to educate patients about their injury so that they have realistic expectations. This is particularly relevant given that the patients most likely to sustain femoral or tibial shaft fractures are working-age healthy adults, and up to a third of fractures may develop delayed union or nonunion.
CONCLUSION: Despite modern treatment, the patient-reported outcomes of lower limb long bone shaft fractures do not return to normal at one year. Patients with delayed union or nonunion can expect poorer outcomes.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Delayed union; Femur; Fracture; Nonunion; Outcomes; Tibia; Trauma

Mesh:

Year:  2014        PMID: 25062602     DOI: 10.1016/j.injury.2014.06.025

Source DB:  PubMed          Journal:  Injury        ISSN: 0020-1383            Impact factor:   2.586


  36 in total

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Authors:  Anthony V Christiano; Christian A Pean; Sanjit R Konda; Kenneth A Egol
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Authors:  Rebecca Mills; Tegan L Cheng; Kathy Mikulec; Lauren Peacock; David Isaacs; Carl Genberg; Paul B Savage; David G Little; Aaron Schindeler
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7.  Radiographic union score for tibia fractures predicts success with operative treatment of tibial nonunion.

Authors:  Anthony V Christiano; Abraham M Goch; Philipp Leucht; Sanjit R Konda; Kenneth A Egol
Journal:  J Clin Orthop Trauma       Date:  2018-10-19

8.  Union Following Biological and Rigid Fixations of Distal Tibia Extra-articular Fractures.

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Review 9.  Recent Advances and Future of Gene Therapy for Bone Regeneration.

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10.  Fracture healing: a consensus report from the International Osteoporosis Foundation Fracture Working Group.

Authors:  S L Silverman; E S Kupperman; S V Bukata
Journal:  Osteoporos Int       Date:  2016-04-25       Impact factor: 4.507

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