Calculated rates of diffusion-limited reactions in a three-dimensional network of connected compartments: application to porous catalysts and biological systems.

We describe the diffusion limit for reaction rates in a three-dimensional system of connected compartments. This model exhibits the length-scale dependent diffusion that can be observed in many heterogeneous environments, such as porous catalysts and biological environments. We obtain a simple analytical expression for the diffusion limit applicable to any scale of the compartment confinement. This diffusion limit exceeds the classic Smoluchowski diffusion limit that was derived for homogeneous environments but is often applied to biological reactions in heterogeneous environments. We expect our new diffusion limit to provide a more appropriate upper bound on reaction rates in biological systems, porous structures, and other heterogeneous environments where obstacles create local confinement.