Literature DB >> 25061519

Evidence based radiation oncology with existing technology.

Nicolas Isa1.   

Abstract

AIM: To assess the real contribution of modern radiation therapy (RT) technology in the more common tumoral types in Central America, Caribbean and South America.
BACKGROUND: RT is an essential tool in the management of cancer. RT can be either palliative or of curative intent. In general, for palliative radiotherapy, major technologies are not needed.
MATERIALS AND METHODS: We analyzed the contribution of RT technology based on published evidence for breast, lung, gastric, gallbladder, colorectal, prostate and cervix cancer in terms of disease control, survival or toxicity with especial focus on Latin America.
RESULTS: Findings indicate that three dimensional conformal radiation therapy (3D RT) is the gold standard in most common type of cancer in the studied regions. Prostate cancer is probably the pathology that has more benefits when using new RT technology such as intensity modulated radiation therapy (IMRT) versus 3DRT in terms of toxicity and biochemical progression-free survival.
CONCLUSIONS: In light of the changes in technology, the ever-increasing access of developing countries to such technology, and its current coverage in Latin America, any efforts in this area should be aimed at improving the quality of the radiotherapy departments and centers that are already in place.

Entities:  

Keywords:  Oncology; Radiation therapy; Technology

Year:  2013        PMID: 25061519      PMCID: PMC4104019          DOI: 10.1016/j.rpor.2013.09.002

Source DB:  PubMed          Journal:  Rep Pract Oncol Radiother        ISSN: 1507-1367


  68 in total

1.  Randomized controlled trial of postoperative radiotherapy and short-term time-scheduled 5-fluorouracil against surgery alone in the treatment of Dukes B and C rectal cancer. Norwegian Adjuvant Rectal Cancer Project Group.

Authors:  K M Tveit; I Guldvog; S Hagen; E Trondsen; T Harbitz; K Nygaard; J B Nilsen; E Wist; E Hannisdal
Journal:  Br J Surg       Date:  1997-08       Impact factor: 6.939

2.  Lymph node control in cervical cancer.

Authors:  Perry W Grigsby; Anurag K Singh; Barry A Siegel; Farrokh Dehdashti; Janet Rader; Imran Zoberi
Journal:  Int J Radiat Oncol Biol Phys       Date:  2004-07-01       Impact factor: 7.038

Review 3.  Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials.

Authors:  M Clarke; R Collins; S Darby; C Davies; P Elphinstone; V Evans; J Godwin; R Gray; C Hicks; S James; E MacKinnon; P McGale; T McHugh; R Peto; C Taylor; Y Wang
Journal:  Lancet       Date:  2005-12-17       Impact factor: 79.321

4.  Nomograms for predicting local recurrence, distant metastases, and overall survival for patients with locally advanced rectal cancer on the basis of European randomized clinical trials.

Authors:  Vincenzo Valentini; Ruud G P M van Stiphout; Guido Lammering; Maria Antonietta Gambacorta; Maria Cristina Barba; Marek Bebenek; Franck Bonnetain; Jean-Francois Bosset; Krzysztof Bujko; Luca Cionini; Jean-Pierre Gerard; Claus Rödel; Aldo Sainato; Rolf Sauer; Bruce D Minsky; Laurence Collette; Philippe Lambin
Journal:  J Clin Oncol       Date:  2011-07-11       Impact factor: 44.544

5.  Phase III trial comparing radical radiotherapy with and without cisplatin chemotherapy in patients with advanced squamous cell cancer of the cervix.

Authors:  R Pearcey; M Brundage; P Drouin; J Jeffrey; D Johnston; H Lukka; G MacLean; L Souhami; G Stuart; D Tu
Journal:  J Clin Oncol       Date:  2002-02-15       Impact factor: 44.544

6.  New perspectives in radiation oncology: Young radiation oncologist point of view and challenges.

Authors:  Jose Luis Lopez Guerra; Nicolas Isa; Michelle M Kim; Celine Bourgier; Hugo Marsiglia
Journal:  Rep Pract Oncol Radiother       Date:  2012-08-09

7.  Adjuvant radiochemotherapy in the treatment of completely resected, locally advanced gastric cancer.

Authors:  M R Baeza; O Giannini T; R Rivera S; P González; J González; E Vergara; C del Castillo; J Madrid; E Vinés
Journal:  Int J Radiat Oncol Biol Phys       Date:  2001-07-01       Impact factor: 7.038

8.  Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer.

Authors:  K Furuse; M Fukuoka; M Kawahara; H Nishikawa; Y Takada; S Kudoh; N Katagami; Y Ariyoshi
Journal:  J Clin Oncol       Date:  1999-09       Impact factor: 44.544

9.  Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix.

Authors:  W A Peters; P Y Liu; R J Barrett; R J Stock; B J Monk; J S Berek; L Souhami; P Grigsby; W Gordon; D S Alberts
Journal:  J Clin Oncol       Date:  2000-04       Impact factor: 44.544

10.  Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03.

Authors:  Mark S Roh; Linda H Colangelo; Michael J O'Connell; Greg Yothers; Melvin Deutsch; Carmen J Allegra; Morton S Kahlenberg; Luis Baez-Diaz; Carol S Ursiny; Nicholas J Petrelli; Norman Wolmark
Journal:  J Clin Oncol       Date:  2009-09-21       Impact factor: 44.544

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  5 in total

Review 1.  Gastric cancer: Current status of lymph node dissection.

Authors:  Maurizio Degiuli; Giovanni De Manzoni; Alberto Di Leo; Domenico D'Ugo; Erica Galasso; Daniele Marrelli; Roberto Petrioli; Karol Polom; Franco Roviello; Francesco Santullo; Mario Morino
Journal:  World J Gastroenterol       Date:  2016-03-14       Impact factor: 5.742

2.  High-risk and low-risk gastric cancer areas in Italy and its association with microsatellite instability.

Authors:  Karol Polom; Daniele Marrelli; Valeria Pascale; Giandomenico Roviello; Costantino Voglino; Henry Rho; Carla Vindigni; Mario Marini; Raffaele Macchiarelli; Franco Roviello
Journal:  J Cancer Res Clin Oncol       Date:  2016-05-20       Impact factor: 4.553

3.  Treatment of limited-stage small cell lung cancer in the elderly, chemotherapy vs. sequential chemoradiotherapy vs. concurrent chemoradiotherapy: that's the question.

Authors:  Cesare Gridelli; Francesca Casaluce; Assunta Sgambato; Fabio Monaco; Cesare Guida
Journal:  Transl Lung Cancer Res       Date:  2016-04

4.  Feasibility of intensity-modulated radiotherapy to treat gastric cancer.

Authors:  Agnieszka Skrobala; Marta Adamczyk; Aldona Karczewska-Dzionk
Journal:  Rep Pract Oncol Radiother       Date:  2018-11-16

5.  The concept of radiation-enhanced stem cell differentiation.

Authors:  Adam A Mieloch; Wiktoria M Suchorska
Journal:  Radiol Oncol       Date:  2015-08-21       Impact factor: 2.991

  5 in total

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