Literature DB >> 25060701

LeA(H)Rning self-control.

Francisco J Quintana1.   

Abstract

The aryl hydrocarbon receptor (AhR) is an important regulator of the immune response. A report by Puccetti and coworkers describes a regulatory pathway by which L-kynurenine (L-Kyn) produced by tryptophan 2,3-dioxygenase 2 (TDO2) activates AhR in cells of the innate immune system to limit endotoxin-triggered inflammation through a mechanism that involves the non-enzymatic anti-inflammatory activities of indoleamine 2,3-dioxygenase 1 (IDO1).

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Year:  2014        PMID： 25060701      PMCID： PMC4185356          DOI： 10.1038/cr.2014.96

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  12 in total

1.  An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells.

Authors:  Joshua D Mezrich; John H Fechner; Xiaoji Zhang; Brian P Johnson; William J Burlingham; Christopher A Bradfield
Journal:  J Immunol       Date:  2010-08-18       Impact factor: 5.422

2.  Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism.

Authors:  Nam Trung Nguyen; Akihiro Kimura; Taisuke Nakahama; Ichino Chinen; Kazuya Masuda; Keiko Nohara; Yoshiaki Fujii-Kuriyama; Tadamitsu Kishimoto
Journal:  Proc Natl Acad Sci U S A       Date:  2010-11-01       Impact factor: 11.205

3.  Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells.

Authors:  Roopali Gandhi; Deepak Kumar; Evan J Burns; Meghan Nadeau; Ben Dake; Alice Laroni; Deneen Kozoriz; Howard L Weiner; Francisco J Quintana
Journal:  Nat Immunol       Date:  2010-08-01       Impact factor: 25.606

Review 4.  Disease tolerance as a defense strategy.

Authors:  Ruslan Medzhitov; David S Schneider; Miguel P Soares
Journal:  Science       Date:  2012-02-24       Impact factor: 47.728

5.  Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells.

Authors:  Maria T Pallotta; Ciriana Orabona; Claudia Volpi; Carmine Vacca; Maria L Belladonna; Roberta Bianchi; Giuseppe Servillo; Cinzia Brunacci; Mario Calvitti; Silvio Bicciato; Emilia M C Mazza; Louis Boon; Fabio Grassi; Maria C Fioretti; Francesca Fallarino; Paolo Puccetti; Ursula Grohmann
Journal:  Nat Immunol       Date:  2011-07-31       Impact factor: 25.606

Review 6.  Aryl hydrocarbon receptor control of adaptive immunity.

Authors:  Francisco J Quintana; David H Sherr
Journal:  Pharmacol Rev       Date:  2013-08-01       Impact factor: 25.468

7.  Aryl hydrocarbon receptor control of a disease tolerance defence pathway.

Authors:  Alban Bessede; Marco Gargaro; Maria T Pallotta; Davide Matino; Giuseppe Servillo; Cinzia Brunacci; Silvio Bicciato; Emilia M C Mazza; Antonio Macchiarulo; Carmine Vacca; Rossana Iannitti; Luciana Tissi; Claudia Volpi; Maria L Belladonna; Ciriana Orabona; Roberta Bianchi; Tobias V Lanz; Michael Platten; Maria A Della Fazia; Danilo Piobbico; Teresa Zelante; Hiroshi Funakoshi; Toshikazu Nakamura; David Gilot; Michael S Denison; Gilles J Guillemin; James B DuHadaway; George C Prendergast; Richard Metz; Michel Geffard; Louis Boon; Matteo Pirro; Alfonso Iorio; Bernard Veyret; Luigina Romani; Ursula Grohmann; Francesca Fallarino; Paolo Puccetti
Journal:  Nature       Date:  2014-07-10       Impact factor: 49.962

8.  The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27.

Authors:  Lionel Apetoh; Francisco J Quintana; Caroline Pot; Nicole Joller; Sheng Xiao; Deepak Kumar; Evan J Burns; David H Sherr; Howard L Weiner; Vijay K Kuchroo
Journal:  Nat Immunol       Date:  2010-08-01       Impact factor: 25.606

9.  Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase.

Authors:  Christoph F A Vogel; Samuel R Goth; Bin Dong; Isaac N Pessah; Fumio Matsumura
Journal:  Biochem Biophys Res Commun       Date:  2008-08-09       Impact factor: 3.575

10.  Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor.

Authors:  Francisco J Quintana; Alexandre S Basso; Antonio H Iglesias; Thomas Korn; Mauricio F Farez; Estelle Bettelli; Mario Caccamo; Mohamed Oukka; Howard L Weiner
Journal:  Nature       Date:  2008-03-23       Impact factor: 49.962
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  6 in total

Review 1.  Dendritic cells and parasites: from recognition and activation to immune response instruction.

Authors:  Claudia Cristina Motran; Laura Fernanda Ambrosio; Ximena Volpini; Daiana Pamela Celias; Laura Cervi
Journal:  Semin Immunopathol       Date:  2016-09-01       Impact factor: 9.623

Review 2.  Dietary and metabolic modulators of hepatic immunity.

Authors:  Antonella Carambia; Johannes Herkel
Journal:  Semin Immunopathol       Date:  2017-11-06       Impact factor: 9.623

3.  TDO2 and tryptophan metabolites promote kynurenine/AhR signals to facilitate glioma progression and immunosuppression.

Authors:  Chuanhong Zhong; Lilei Peng; Bei Tao; Senlin Yin; Liang Lyu; Hao Ding; Xiaobo Yang; Tangming Peng; Haiping He; Peizhi Zhou
Journal:  Am J Cancer Res       Date:  2022-06-15       Impact factor: 5.942

Review 4.  Regulation of the Immune Response by the Aryl Hydrocarbon Receptor.

Authors:  Cristina Gutiérrez-Vázquez; Francisco J Quintana
Journal:  Immunity       Date:  2018-01-16       Impact factor: 31.745

Review 5.  The aryl hydrocarbon receptor: a review of its role in the physiology and pathology of the integument and its relationship to the tryptophan metabolism.

Authors:  Rowland Noakes
Journal:  Int J Tryptophan Res       Date:  2015-02-10

Review 6.  The Role of the Aryl Hydrocarbon Receptor (AHR) in Immune and Inflammatory Diseases.

Authors:  Drew R Neavin; Duan Liu; Balmiki Ray; Richard M Weinshilboum
Journal:  Int J Mol Sci       Date:  2018-12-03       Impact factor: 5.923
  6 in total

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