Literature DB >> 25060632

MicroRNA and signaling pathways in gastric cancer.

Z Zhang1, Z Li1, Y Li2, A Zang1.   

Abstract

MicroRNAs (miRNAs) function as either oncogenes or tumor suppressors by inhibiting the expression of target genes, some of which are either directly or indirectly involved with canonical signaling pathways. The relationship between miRNAs and signaling pathways in gastric cancer is extremely complicated. In this paper, we determined the pathogenic mechanism of gastric cancer related to miRNA expression based on recent high-quality studies and then clarified the regulation network of miRNA expression and the correlated functions of these miRNAs during the progression of gastric cancer. We try to illustrate the correlation between the expression of miRNAs and outcomes of patients with gastric cancer. Understanding this will allow us to take a big step forward in the treatment of gastric cancer.

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Year:  2014        PMID： 25060632     DOI： 10.1038/cgt.2014.37

Source DB:  PubMed          Journal:  Cancer Gene Ther        ISSN： 0929-1903            Impact factor:   5.987


  203 in total

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  22 in total

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Review 5.  Treatment Strategies of Gastric Cancer-Molecular Targets for Anti-angiogenic Therapy: a State-of-the-art Review.

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7.  Differential MicroRNA Expression Between Gastric Cancer Tissue and Non-cancerous Gastric Mucosa According to Helicobacter pylori Status.

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Journal:  J Cancer Prev       Date:  2017-03-30

Review 8.  Role of microRNAs and Exosomes in Helicobacter pylori and Epstein-Barr Virus Associated Gastric Cancers.

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10.  GCGene: a gene resource for gastric cancer with literature evidence.

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Journal:  Oncotarget       Date:  2016-06-07
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