Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Cutting it out: ENaC processing in the human nephron.

Literature DB >> 25060054

Cutting it out: ENaC processing in the human nephron.

Evan C Ray¹, Thomas R Kleyman².

Abstract

Entities: Species

Keywords: ENaC; plasmin; prostasin; protease

Mesh：

Substances：

Year: 2014 PMID： 25060054 PMCID： PMC4279749 DOI： 10.1681/ASN.2014060618

Source DB: PubMed Journal: J Am Soc Nephrol ISSN： 1046-6673 Impact factor: 10.121

× No keyword cloud information.

15 in total

1. Maturation of the epithelial Na+ channel involves proteolytic processing of the alpha- and gamma-subunits.

Authors: Rebecca P Hughey; Gunhild M Mueller; James B Bruns; Carol L Kinlough; Paul A Poland; Keri L Harkleroad; Marcelo D Carattino; Thomas R Kleyman
Journal: J Biol Chem Date: 2003-07-18 Impact factor: 5.157

2. Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit.

Authors: James B Bruns; Marcelo D Carattino; Shaohu Sheng; Ahmad B Maarouf; Ora A Weisz; Joseph M Pilewski; Rebecca P Hughey; Thomas R Kleyman
Journal: J Biol Chem Date: 2007-01-01 Impact factor: 5.157

Review 3. ENaC at the cutting edge: regulation of epithelial sodium channels by proteases.

Authors: Thomas R Kleyman; Marcelo D Carattino; Rebecca P Hughey
Journal: J Biol Chem Date: 2009-04-28 Impact factor: 5.157

4. Proteolytic processing of the epithelial sodium channel gamma subunit has a dominant role in channel activation.

Authors: Marcelo D Carattino; Rebecca P Hughey; Thomas R Kleyman
Journal: J Biol Chem Date: 2008-07-23 Impact factor: 5.157

5. Plasmin in nephrotic urine activates the epithelial sodium channel.

Authors: Per Svenningsen; Claus Bistrup; Ulla G Friis; Marko Bertog; Silke Haerteis; Bettina Krueger; Jane Stubbe; Ole Nørregaard Jensen; Helle C Thiesson; Torben R Uhrenholt; Bente Jespersen; Boye L Jensen; Christoph Korbmacher; Ole Skøtt
Journal: J Am Soc Nephrol Date: 2008-12-10 Impact factor: 10.121

6. Plasmin activates epithelial Na+ channels by cleaving the gamma subunit.

Authors: Christopher J Passero; Gunhild M Mueller; Helbert Rondon-Berrios; Stevan P Tofovic; Rebecca P Hughey; Thomas R Kleyman
Journal: J Biol Chem Date: 2008-11-03 Impact factor: 5.157

7. Regulation of maturation and processing of ENaC subunits in the rat kidney.

Authors: Zuhal Ergonul; Gustavo Frindt; Lawrence G Palmer
Journal: Am J Physiol Renal Physiol Date: 2006-03-22

8. Surface expression of sodium channels and transporters in rat kidney: effects of dietary sodium.

Authors: Gustavo Frindt; Lawrence G Palmer
Journal: Am J Physiol Renal Physiol Date: 2009-09-09

9. Defective ENaC processing and function in tissue kallikrein-deficient mice.

Authors: Nicolas Picard; Dominique Eladari; Soumaya El Moghrabi; Carole Planès; Soline Bourgeois; Pascal Houillier; Qing Wang; Michel Burnier; Georges Deschenes; Mark A Knepper; Pierre Meneton; Régine Chambrey
Journal: J Biol Chem Date: 2007-12-17 Impact factor: 5.157

Cutting it out: ENaC processing in the human nephron.

1. Maturation of the epithelial Na+ channel involves proteolytic processing of the alpha- and gamma-subunits.

2. Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit.

Review 3. ENaC at the cutting edge: regulation of epithelial sodium channels by proteases.

4. Proteolytic processing of the epithelial sodium channel gamma subunit has a dominant role in channel activation.

5. Plasmin in nephrotic urine activates the epithelial sodium channel.

6. Plasmin activates epithelial Na+ channels by cleaving the gamma subunit.

7. Regulation of maturation and processing of ENaC subunits in the rat kidney.

8. Surface expression of sodium channels and transporters in rat kidney: effects of dietary sodium.

9. Defective ENaC processing and function in tissue kallikrein-deficient mice.

10. ENaC proteolytic regulation by channel-activating protease 2.

Review 1. Protease-activated receptors in kidney disease progression.

Review 2. Epithelial Na⁺ Channel Regulation by Extracellular and Intracellular Factors.

3. Chronic cathepsin inhibition by E-64 in Dahl salt-sensitive rats.

4. Optimization of Normal Human Bronchial Epithelial (NHBE) Cell 3D Cultures for in vitro Lung Model Studies.

5. Dietary sodium modulates nephropathy in Nedd4-2-deficient mice.

6. Renal sodium transport in renin-deficient Dahl salt-sensitive rats.

7. Urinary Plasmin(ogen) as a Prognostic Factor for Hypertension.

Review 3. ENaC at the cutting edge: regulation of epithelial sodium channels by proteases.

Review 1. Protease-activated receptors in kidney disease progression.

Review 2. Epithelial Na+ Channel Regulation by Extracellular and Intracellular Factors.

Review 2. Epithelial Na⁺ Channel Regulation by Extracellular and Intracellular Factors.