Literature DB >> 2505906

Effects of intracellular diphosphonates on cells of the mononuclear phagocyte system: in vivo effects of liposome-encapsulated diphosphonates on different macrophage subpopulations in the spleen.

N van Rooijen1, N Kors.   

Abstract

The intracellular effects of different diphosphonates on splenic macrophages were compared after intravenous injection of liposomes with encapsulated dichloromethylene diphosphonate (C12MDP), 3-amino-1-hydroxypropane-1,1-diphosphonate (APD), or 1 hydroxyethane-1,1-diphosphonate (EHDP) in similar concentrations. Intracellular C12MDP was by far the most toxic compound for macrophages in the spleen. APD encapsulated in liposomes in the highest possible concentration eliminated marginal zone macrophages only and EHDP did not affect any of the macrophage subpopulations in the spleen.

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Year:  1989        PMID： 2505906     DOI： 10.1007/bf02556058

Source DB:  PubMed          Journal:  Calcif Tissue Int        ISSN： 0171-967X            Impact factor:   4.333


  8 in total

1.  Marginal metallophilic cells of the mouse spleen identified by a monoclonal antibody.

Authors:  G Kraal; M Janse
Journal:  Immunology       Date:  1986-08       Impact factor: 7.397

2.  Macrophages in T and B cell compartments and other tissue macrophages recognized by monoclonal antibody MOMA-2. An immunohistochemical study.

Authors:  G Kraal; M Rep; M Janse
Journal:  Scand J Immunol       Date:  1987-12       Impact factor: 3.487

3.  Marginal zone macrophages in the mouse spleen identified by a monoclonal antibody. Anatomical correlation with a B cell subpopulation.

Authors:  E van Vliet; M Melis; W van Ewijk
Journal:  J Histochem Cytochem       Date:  1985-01       Impact factor: 2.479

4.  Marginal zone macrophages identified by a monoclonal antibody: characterization of immuno- and enzyme-histochemical properties and functional capacities.

Authors:  C D Dijkstra; E Van Vliet; E A Döpp; A A van der Lelij; G Kraal
Journal:  Immunology       Date:  1985-05       Impact factor: 7.397

Review 5.  Bisphosphonates--history and experimental basis.

Authors:  H Fleisch
Journal:  Bone       Date:  1987       Impact factor: 4.398

6.  Elimination of phagocytic cells in the spleen after intravenous injection of liposome-encapsulated dichloromethylene diphosphonate. Ultrastructural aspects of elimination of marginal zone macrophages.

Authors:  N van Rooijen; R van Nieuwmegen; E W Kamperdijk
Journal:  Virchows Arch B Cell Pathol Incl Mol Pathol       Date:  1985

7.  Elimination of phagocytic cells in the spleen after intravenous injection of liposome-encapsulated dichloromethylene diphosphonate. An enzyme-histochemical study.

Authors:  N van Rooijen; R van Nieuwmegen
Journal:  Cell Tissue Res       Date:  1984       Impact factor: 5.249

8.  Macrophage subset repopulation in the spleen: differential kinetics after liposome-mediated elimination.

Authors:  N van Rooijen; N Kors; G Kraal
Journal:  J Leukoc Biol       Date:  1989-02       Impact factor: 4.962
  8 in total
  5 in total

1.  Contrast between effects of aminobisphosphonates and non-aminobisphosphonates on collagen-induced arthritis in mice.

Authors:  M Nakamura; T Ando; M Abe; K Kumagai; Y Endo
Journal:  Br J Pharmacol       Date:  1996-09       Impact factor: 8.739

Review 2.  Extracellular and intracellular action of clodronate in osteolytic bone diseases? A hypothesis.

Authors:  N van Rooijen
Journal:  Calcif Tissue Int       Date:  1993-06       Impact factor: 4.333

3.  Aminoalkylbisphosphonates, potent inhibitors of bone resorption, induce a prolonged stimulation of histamine synthesis and increase macrophages, granulocytes, and osteoclasts in vivo.

Authors:  Y Endo; M Nakamura; T Kikuchi; H Shinoda; Y Takeda; Y Nitta; K Kumagai
Journal:  Calcif Tissue Int       Date:  1993-03       Impact factor: 4.333

4.  Incorporation of bisphosphonates into adenine nucleotides by amoebae of the cellular slime mould Dictyostelium discoideum.

Authors:  M J Rogers; X Ji; R G Russell; G M Blackburn; M P Williamson; A V Bayless; F H Ebetino; D J Watts
Journal:  Biochem J       Date:  1994-10-01       Impact factor: 3.857

5.  Increased Plasmodium falciparum Parasitemia in Non-splenectomized Saimiri sciureus Monkeys Treated with Clodronate Liposomes.

Authors:  Janaiara A Cunha; Leonardo J M Carvalho; Cesare Bianco-Junior; Márcia C R Andrade; Lilian R Pratt-Riccio; Evelyn K P Riccio; Marcelo Pelajo-Machado; Igor J da Silva; Pierre Druilhe; Cláudio Tadeu Daniel-Ribeiro
Journal:  Front Cell Infect Microbiol       Date:  2017-09-21       Impact factor: 5.293
  5 in total

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