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Literature DB >> 25057977

Medical management of meningiomas.

Abstract

The efficacy of surgery and radiation has been well validated in the treatment of meningiomas, with efficacy depending on tumor pathology, size, symptomatology and rate of progression. The role of medical therapy has the least amount of data but is being increasingly investigated for tumors that are inoperable or those tumors that recur and/or progress despite standard therapy. In this review, current data on the use of chemotherapeutic agents in the management of meningiomas will be reviewed, including cytotoxic, biologic, targeted molecular and hormonal agents.

Entities: Disease

Mesh：

Substances：
Antineoplastic Agents

Year: 2013 PMID： 25057977 PMCID： PMC6169485 DOI： 10.2217/cns.13.6

Source DB: PubMed Journal: CNS Oncol ISSN： 2045-0907

69 in total

1. Expression and activation of epidermal growth factor receptors in meningiomas.

Authors: R S Carroll; P M Black; J Zhang; M Kirsch; I Percec; N Lau; A Guha
Journal: J Neurosurg Date: 1997-08 Impact factor: 5.115

2. Growth of a meningioma in a transsexual patient after estrogen-progestin therapy.

Authors: Roberto Gazzeri; Marcelo Galarza; Giovanni Gazzeri
Journal: N Engl J Med Date: 2007-12-06 Impact factor: 91.245

3. Evidence for phosphatidylinositol 3-kinase-Akt-p7S6K pathway activation and transduction of mitogenic signals by platelet-derived growth factor in meningioma cells.

Authors: Mahlon D Johnson; Evelyn Okedli; Ann Woodard; Steven A Toms; George S Allen
Journal: J Neurosurg Date: 2002-09 Impact factor: 5.115

4. The treatment of recurrent unresectable and malignant meningiomas with interferon alpha-2B.

Authors: S E Kaba; F DeMonte; J M Bruner; A P Kyritsis; K A Jaeckle; V Levin; W K Yung
Journal: Neurosurgery Date: 1997-02 Impact factor: 4.654

Review 5. Medical therapies for meningiomas.

Authors: Patrick Y Wen; Eudocia Quant; Jan Drappatz; Rameen Beroukhim; Andrew D Norden
Journal: J Neurooncol Date: 2010-09-04 Impact factor: 4.130

6. Hydroxyurea for treatment of unresectable and recurrent meningiomas. II. Decrease in the size of meningiomas in patients treated with hydroxyurea.

Authors: U M Schrell; M G Rittig; M Anders; U H Koch; R Marschalek; F Kiesewetter; R Fahlbusch
Journal: J Neurosurg Date: 1997-05 Impact factor: 5.115

7. Epidermal growth factor receptor expression in 72 meningiomas.

Authors: N R Jones; M L Rossi; M Gregoriou; J T Hughes
Journal: Cancer Date: 1990-07-01 Impact factor: 6.860

8. Long-term recurrence rates of atypical meningiomas after gross total resection with or without postoperative adjuvant radiation.

Authors: Manish K Aghi; Bob S Carter; Garth R Cosgrove; Robert G Ojemann; Sepideh Amin-Hanjani; Robert L Martuza; William T Curry; Fred G Barker
Journal: Neurosurgery Date: 2009-01 Impact factor: 4.654

9. The role of radiotherapy following gross-total resection of atypical meningiomas.

Authors: Ricardo J Komotar; J Bryan Iorgulescu; Daniel M S Raper; Eric C Holland; Kathryn Beal; Mark H Bilsky; Cameron W Brennan; Viviane Tabar; Jonathan H Sherman; Yoshiya Yamada; Philip H Gutin
Journal: J Neurosurg Date: 2012-08-24 Impact factor: 5.115