| Literature DB >> 25055921 |
Harsh Dweep1, Norbert Gretz, Kyriakos Felekkis.
Abstract
MicroRNAs (miRNAs) and copy number variations (CNVs) are two extensively studied genomic components in the field of modern biology-as they have been found to be associated with many disorders such as cancer, Alzheimer, pancreatitis, HIV susceptibility, beta-thalassemia, and glomerulonephritis. Several studies suggested that an alteration in CNV-miRNA interaction could result in some human diseases such as cancer. Therefore, the possible miRNA-binding site information within the CNV genes opens new avenues in understanding such disorders. In this chapter, we present a schematic approach for collecting the information on CNV-miRNA interactions using miRWalk and TargetScan databases.Entities:
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Year: 2014 PMID: 25055921 DOI: 10.1007/978-1-4939-1062-5_26
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745