Literature DB >> 25055921

A schematic workflow for collecting information about the interaction between copy number variants and microRNAs using existing resources.

Harsh Dweep1, Norbert Gretz, Kyriakos Felekkis.   

Abstract

MicroRNAs (miRNAs) and copy number variations (CNVs) are two extensively studied genomic components in the field of modern biology-as they have been found to be associated with many disorders such as cancer, Alzheimer, pancreatitis, HIV susceptibility, beta-thalassemia, and glomerulonephritis. Several studies suggested that an alteration in CNV-miRNA interaction could result in some human diseases such as cancer. Therefore, the possible miRNA-binding site information within the CNV genes opens new avenues in understanding such disorders. In this chapter, we present a schematic approach for collecting the information on CNV-miRNA interactions using miRWalk and TargetScan databases.

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Year:  2014        PMID: 25055921     DOI: 10.1007/978-1-4939-1062-5_26

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  4 in total

1.  Integrated microRNA-mRNA Expression Profiling Identifies Novel Targets and Networks Associated with Autism.

Authors:  Pritmohinder S Gill; Harsh Dweep; Shannon Rose; Priyankara J Wickramasinghe; Kanan K Vyas; Sandra McCullough; Patricia A Porter-Gill; Richard E Frye
Journal:  J Pers Med       Date:  2022-06-01

2.  Homo sapiens exhibit a distinct pattern of CNV genes regulation: an important role of miRNAs and SNPs in expression plasticity.

Authors:  Harsh Dweep; Nada Kubikova; Norbert Gretz; Konstantinos Voskarides; Kyriacos Felekkis
Journal:  Sci Rep       Date:  2015-07-16       Impact factor: 4.379

3.  Polymorphisms in miRNAs Gene (146a, 149, 196a) and Susceptibility to ARV-associated Hepatotoxicity.

Authors:  Hari Om Singh; Sushma Jadhav; Dharmesh Samani; Tapan N Dhole
Journal:  Curr Genomics       Date:  2019-02       Impact factor: 2.236

4.  A Comprehensive Review on the Genetic Regulation of Cisplatin-induced Nephrotoxicity.

Authors:  Zeneida Herrera-Pérez; Norbert Gretz; Harsh Dweep
Journal:  Curr Genomics       Date:  2016-06       Impact factor: 2.236

  4 in total

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