Literature DB >> 25055056

Label-free immunodetection of the cancer biomarker CA125 using high-Δn liquid crystals.

Hui-Wen Su1, Yun-Han Lee1, Mon-Juan Lee2, Yi-Chiang Hsu3, Wei Lee1.   

Abstract

A label-free and array-based optical liquid-crystal (LC) immunodetection technique for the detection of CA125 antigen, a protein biomarker most frequently used for ovarian cancer detection, was demonstrated with a nematic LC with larger birefringence (Δn) to promote sensitivity in detecting biomolecules. The LC-based immunodetection offers an alternative and sensitive approach for the detection of biomarker proteins, with the potential of replacing conventional immunoassays used in biochemical studies and clinical laboratories.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 25055056     DOI： 10.1117/1.JBO.19.7.077006

Source DB:  PubMed          Journal:  J Biomed Opt        ISSN： 1083-3668            Impact factor:   3.170


  12 in total

1.  Highly sensitive color-indicating and quantitative biosensor based on cholesteric liquid crystal.

Authors:  Yu-Cheng Hsiao; Yu-Chien Sung; Mon-Juan Lee; Wei Lee
Journal:  Biomed Opt Express       Date:  2015-11-23       Impact factor: 3.732

2.  Immunoassays for the cancer biomarker CA125 based on a large-birefringence nematic liquid-crystal mixture.

Authors:  Shih-Hung Sun; Mon-Juan Lee; Yun-Han Lee; Wei Lee; Xiaolong Song; Chao-Yuan Chen
Journal:  Biomed Opt Express       Date:  2014-12-23       Impact factor: 3.732

3.  Label-free protein sensing by employing blue phase liquid crystal.

Authors:  Mon-Juan Lee; Chung-Huan Chang; Wei Lee
Journal:  Biomed Opt Express       Date:  2017-02-21       Impact factor: 3.732

4.  Electric-field-assisted signal amplification for label-free liquid-crystal-based detection of biomolecules.

Authors:  Wei-Liang Hsu; Mon-Juan Lee; Wei Lee
Journal:  Biomed Opt Express       Date:  2019-09-06       Impact factor: 3.732

5.  Label-free, color-indicating, and sensitive biosensors of cholesteric liquid crystals on a single vertically aligned substrate.

Authors:  Fu-Lun Chen; Yu-Jui Fan; Jia-De Lin; Yu-Cheng Hsiao
Journal:  Biomed Opt Express       Date:  2019-08-19       Impact factor: 3.732

Review 6.  Liquid Crystals: A Novel Approach for Cancer Detection and Treatment.

Authors:  Jayalakshmi Vallamkondu; Edwin Bernard Corgiat; Gollapelli Buchaiah; Ramesh Kandimalla; P Hemachandra Reddy
Journal:  Cancers (Basel)       Date:  2018-11-21       Impact factor: 6.639

Review 7.  Spotlight on Biomimetic Systems Based on Lyotropic Liquid Crystal.

Authors:  Juliana F de Souza; Katiusca da S Pontes; Thais F R Alves; Venâncio A Amaral; Márcia de A Rebelo; Moema A Hausen; Marco V Chaud
Journal:  Molecules       Date:  2017-03-07       Impact factor: 4.411

8.  Label-Free, Smartphone-Based, and Sensitive Nano-Structural Liquid Crystal Aligned by Ceramic Silicon Compound-Constructed DMOAP-Based Biosensor for the Detection of Urine Albumin.

Authors:  Er-Yuan Chuang; Ping-Yuan Lin; Po-Feng Wang; Tsung-Rong Kuo; Chih-Hwa Chen; Yankuba B Manga; Yu-Cheng Hsiao
Journal:  Int J Nanomedicine       Date:  2021-02-04

9.  A Single-Substrate Biosensor with Spin-Coated Liquid Crystal Film for Simple, Sensitive and Label-Free Protein Detection.

Authors:  Po-Chang Wu; Chao-Ping Pai; Mon-Juan Lee; Wei Lee
Journal:  Biosensors (Basel)       Date:  2021-10-06

10.  Signal Amplification in an Optical and Dielectric Biosensor Employing Liquid Crystal-Photopolymer Composite as the Sensing Medium.

Authors:  Hassanein Shaban; Shih-Chun Yen; Mon-Juan Lee; Wei Lee
Journal:  Biosensors (Basel)       Date:  2021-03-13
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.