Literature DB >> 25054009

Anti-inflammatory effects of ozonated water in an experimental mouse model.

Kazuo Azuma1, Takuro Mori1, Kinya Kawamoto1, Kohei Kuroda1, Takeshi Tsuka1, Tomohiro Imagawa1, Tomohiro Osaki1, Fumio Itoh2, Saburo Minami1, Yoshiharu Okamoto1.   

Abstract

Previous studies have suggested that ozonated water is safe and possesses antibacterial effects for treatment of experimental peritonitis rats. In this study, we evaluated the anti-inflammatory effects of ozonated water that was intraperitoneally injected into an experimental inflammatory mouse model. The concentrations of dissolved ozone decreased constantly and lineally, while the half-life of dissolved ozone was 36.8±2.7 min (27°C). The 10-ppm ozonated water was injected intraperitoneally into mice with lipopolysaccharide (LPS)-induced acute inflammation. The results showed that the intraperitoneal injection of ozonated water decreased the levels of tumor necrosis factor-α (TNF-α) and increased the activity of superoxide dismutase (SOD). The results suggest that ozonated water has anti-inflammatory properties and is a potential therapeutic option for acute inflammation.

Entities:  

Keywords:  anti-inflammatory; mouse; ozonated water; tumor necrosis factor-α

Year:  2014        PMID： 25054009      PMCID： PMC4106612          DOI： 10.3892/br.2014.290

Source DB:  PubMed          Journal:  Biomed Rep        ISSN： 2049-9434


  34 in total

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Journal:  Epidemiology       Date:  2005-07       Impact factor: 4.822

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Journal:  Epidemiology       Date:  2005-11       Impact factor: 4.822

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  7 in total

1.  The effects of ozone therapy on caspase pathways, TNF-α, and HIF-1α in diabetic nephropathy.

Authors:  Aydın Güçlü; Haydar Ali Erken; Gülten Erken; Yavuz Dodurga; Arzu Yay; Özge Özçoban; Hasan Şimşek; Aydın Akçılar; Fatma Emel Koçak
Journal:  Int Urol Nephrol       Date:  2015-11-27       Impact factor: 2.370

2.  Randomized controlled clinical trial on bleaching sensitivity and whitening efficacy of hydrogen peroxide versus combinations of hydrogen peroxide and ozone.

Authors:  Mahmoud K Al-Omiri; Abdullah A Al Nazeh; Andrej M Kielbassa; Edward Lynch
Journal:  Sci Rep       Date:  2018-02-05       Impact factor: 4.379

3.  Ozone ultrafine bubble water inhibits the early formation of Candida albicans biofilms.

Authors:  Yuka Shichiri-Negoro; Chiaki Tsutsumi-Arai; Yuki Arai; Kazuhito Satomura; Shinichi Arakawa; Noriyuki Wakabayashi
Journal:  PLoS One       Date:  2021-12-10       Impact factor: 3.240

4.  Treatment of symptomatic, deep, almost cariously exposed lesions using ozone.

Authors:  Mahmoud K Al-Omiri; Nasser M Alqahtani; Nasser M Alahmari; Raed Abul Hassan; Abdullah A Al Nazeh; Edward Lynch
Journal:  Sci Rep       Date:  2021-05-27       Impact factor: 4.379

5.  The Safety and Anti-Tumor Effects of Ozonated Water in Vivo.

Authors:  Kohei Kuroda; Kazuo Azuma; Takuro Mori; Kinya Kawamoto; Yusuke Murahata; Takeshi Tsuka; Tomohiro Osaki; Norihiko Ito; Tomohiro Imagawa; Fumio Itoh; Yoshiharu Okamoto
Journal:  Int J Mol Sci       Date:  2015-10-22       Impact factor: 5.923

6.  Ozone- A Biological Therapy in Dentistry- Reality or Myth?????

Authors:  Saraswathi V Naik; Rajeshwari K; Shivani Kohli; Sayyad Zohabhasan; Shekhar Bhatia
Journal:  Open Dent J       Date:  2016-05-11

7.  Evaluation of the antibacterial activity of a new ozonized olive oil against oral and periodontal pathogens.

Authors:  Giampiero Pietrocola; Matteo Ceci; Francesco Preda; Claudio Poggio; Marco Colombo
Journal:  J Clin Exp Dent       Date:  2018-11-01
  7 in total

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