Literature DB >> 25053694

Treatment of complex infantile haemangioma in a resource-poor setting.

Ronald Natawidjaja1, Ewen Wang2.   

Abstract

Infantile haemangiomas affect approximately 5% of the population and usually do not require treatment. However, complex cutaneous haemangiomas can cause disabling disfigurement, while haemangiomas in the brain, airway or gastrointestinal tract can cause life-threatening complications. Although children with infantile haemangiomas are often first brought to general practitioners and paediatricians by parents for care, they are thought of as a surgical problem and usually referred to specialty care. We present a case of an infant from a resource-poor setting in rural Indonesia with disfiguring facial haemangiomas, as well as a probable airway haemangioma causing stridor at rest. The infant was treated with oral propranolol with marked involution of the cutaneous haemangioma, resolution of stridor and increase in weight. 2014 BMJ Publishing Group Ltd.

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Year:  2014        PMID: 25053694      PMCID: PMC4112300          DOI: 10.1136/bcr-2014-205330

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  12 in total

Review 1.  Hemangiomas in children.

Authors:  B A Drolet; N B Esterly; I J Frieden
Journal:  N Engl J Med       Date:  1999-07-15       Impact factor: 91.245

Review 2.  Propranolol for infantile haemangiomas: insights into the molecular mechanisms of action.

Authors:  C H Storch; P H Hoeger
Journal:  Br J Dermatol       Date:  2010-05-08       Impact factor: 9.302

3.  Life-threatening infantile haemangioma: a dramatic response to propranolol.

Authors:  T Theletsane; A Redfern; O Raynham; T Harris; N S Prose; N P Khumalo
Journal:  J Eur Acad Dermatol Venereol       Date:  2009-05-06       Impact factor: 6.166

4.  Propranolol for severe hemangiomas of infancy.

Authors:  Christine Léauté-Labrèze; Eric Dumas de la Roque; Thomas Hubiche; Franck Boralevi; Jean-Benoît Thambo; Alain Taïeb
Journal:  N Engl J Med       Date:  2008-06-12       Impact factor: 91.245

5.  Efficacy of propranolol in hepatic infantile hemangiomas with diffuse neonatal hemangiomatosis.

Authors:  Juliette Mazereeuw-Hautier; Peter H Hoeger; Sarah Benlahrech; Amir Ammour; Pierre Broue; Julie Vial; Gerard Ohanessian; Christine Léauté-Labrèze; Marc Labenne; Pierre Vabres; Jochen Rössler; Christine Bodemer
Journal:  J Pediatr       Date:  2010-05-20       Impact factor: 4.406

6.  Propranolol treatment for severe infantile hemangiomas: a single-centre 3-year experience.

Authors:  Anastasia Georgountzou; Emmanouil Karavitakis; Alexandra Klimentopoulou; Athina Xaidara; Talia Kakourou
Journal:  Acta Paediatr       Date:  2012-07-24       Impact factor: 2.299

7.  Propranolol vs corticosteroids for infantile hemangiomas: a multicenter retrospective analysis.

Authors:  Cynthia J Price; Carol Lattouf; Bertha Baum; Michael McLeod; Lawrence A Schachner; Ana M Duarte; Elizabeth Alvarez Connelly
Journal:  Arch Dermatol       Date:  2011-08-15

8.  Propranolol versus prednisone in the treatment of infantile hemangiomas: a retrospective comparative study.

Authors:  Janie Bertrand; Catherine McCuaig; Josée Dubois; Afshin Hatami; Sandra Ondrejchak; Julie Powell
Journal:  Pediatr Dermatol       Date:  2011-10-13       Impact factor: 1.588

9.  Propranolol therapy in 55 infants with infantile hemangioma: dosage, duration, adverse effects, and outcome.

Authors:  Christine J Schupp; Johann-Baptist Kleber; Patrick Günther; Stefan Holland-Cunz
Journal:  Pediatr Dermatol       Date:  2011-10-13       Impact factor: 1.588

Review 10.  Treatment of infantile hemangiomas with beta-blockers: a review.

Authors:  Sonal Shah; Ilona J Frieden
Journal:  Skin Therapy Lett       Date:  2013 Sep-Oct
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