Y Zhu 1 , W Chen 1 , T Sun 1 , X Zhang 1 , S Liu 1 , Y Zhang 2 Show Affiliations »
Abstract
BACKGROUND AND AIMS: A systematic review and meta-analysis was performed to investigate the risk factors associated with periprosthetic fracture after total hip arthroplasty. MATERIAL AND METHODS: We searched potential studies in the following databases: MEDLINE, Embase, Web of Science, SCOPUS and Cochrane CENTRAL up to December 2013. Newcastle-Ottawa Scale was used to evaluate the methodological quality, and Stata 11.0 was used to perform all the analyses. RESULTS: Seven studies altogether, including 1069 cases of periprosthetic fractures and 74,776 controls, were included in the meta-analysis. Compared to those absent following demographic or medical conditions, patients involved with female gender (odds ratio, 1.534; p < 0.001), advanced age (>80) (odds ratio: 4.203; p < 0.001), revision (odds ratio: 4.398; p < 0.001), rheumatoid arthritis (odds ratio: 2.503; p < 0.001), osteonecrosis (odds ratio: 1.563; p = 0.009), and implant type of Exeter (odds ratio: 1.511; p = 0.017) were more likely to sustain periprosthetic fractures. Osteoarthritis (vs not) (odds ratio: 0.449; p < 0.001) was identified a protective factor for periprosthetic fractures after total hip arthroplasty. The other factors, including lower ages, American Society of Anesthesiologists ≥ 3, and other implant types, were not significant risk factors for periprosthetic fractures. CONCLUSIONS: These medical conditions as reminder should be kept in clinicians' mind and close follow-up should be implemented in patients involved for preventing the occurrence of periprosthetic fractures after total hip arthroplasty. © The Finnish Surgical Society 2014.
BACKGROUND AND AIMS: A systematic review and meta-analysis was performed to investigate the risk factors associated with periprosthetic fracture after total hip arthroplasty . MATERIAL AND METHODS: We searched potential studies in the following databases: MEDLINE, Embase, Web of Science, SCOPUS and Cochrane CENTRAL up to December 2013. Newcastle-Ottawa Scale was used to evaluate the methodological quality, and Stata 11.0 was used to perform all the analyses. RESULTS: Seven studies altogether, including 1069 cases of periprosthetic fractures and 74,776 controls, were included in the meta-analysis. Compared to those absent following demographic or medical conditions, patients involved with female gender (odds ratio, 1.534; p < 0.001), advanced age (>80) (odds ratio: 4.203; p < 0.001), revision (odds ratio: 4.398; p < 0.001), rheumatoid arthritis (odds ratio: 2.503; p < 0.001), osteonecrosis (odds ratio: 1.563; p = 0.009), and implant type of Exeter (odds ratio: 1.511; p = 0.017) were more likely to sustain periprosthetic fractures . Osteoarthritis (vs not) (odds ratio: 0.449; p < 0.001) was identified a protective factor for periprosthetic fractures after total hip arthroplasty . The other factors, including lower ages, American Society of Anesthesiologists ≥ 3, and other implant types, were not significant risk factors for periprosthetic fractures . CONCLUSIONS: These medical conditions as reminder should be kept in clinicians' mind and close follow-up should be implemented in patients involved for preventing the occurrence of periprosthetic fractures after total hip arthroplasty . © The Finnish Surgical Society 2014.
Entities: Disease
Species
Keywords:
Risk factors; meta-analysis; periprosthetic fracture; systematic review; total hip arthroplasty
Mesh： See more »
Year: 2014
PMID： 25053584 DOI： 10.1177/1457496914543979
Source DB: PubMed Journal: Scand J Surg ISSN： 1457-4969 Impact factor: 2.360