Advances in nonsurgical treatment of benign thyroid nodules.

Ethanol ablation has traditionally been used for treatment of cystic thyroid nodules. Laser ablation and radiofrequency ablation were introduced later and used for treatment of solid thyroid nodules. However, how to select the best treatment modality among the different techniques has, so far, not been determined and causes confusion in clinical practice. Therefore, the necessity for a proper guideline regarding the choice of the preferable treatment modality has been suggested as the use of nonsurgical treatment for benign thyroid nodules has been increasing. This article provides an up-to-date review of nonsurgical treatment of benign thyroid nodules focusing on how to select the best treatment modality according to the composition of thyroid nodules based on the clinical evidence.