Literature DB >> 25051905

Advance distribution of misoprostol for the prevention of postpartum hemorrhage in South Sudan.

Jeffrey M Smith1, Alexander Dimiti2, Vikas Dwivedi3, Isabella Ochieng4, Maryrose Dalaka5, Sheena Currie6, Edward Eremugo Luka4, John Rumunu7, Solomon Orero4, Jaime Mungia8, Catharine McKaig4.   

Abstract

OBJECTIVE: To determine if high uterotonic coverage can be achieved in South Sudan through a facility- and community-focused postpartum hemorrhage (PPH) prevention program.
METHODS: The program was implemented from October 2012 to March 2013. At health facilities, active management of the third stage of labor (AMTSL) was emphasized. During prenatal care and home visits, misoprostol was distributed to pregnant women at approximately 32 weeks of pregnancy for the prevention of PPH at home births. Data on uterotonic coverage and other program outcomes were collected through facility registers, home visits, and postpartum interviews.
RESULTS: In total, 533 home births and 394 facility-based births were reported. Misoprostol was distributed in advance to 787 (84.9%) pregnant women, of whom 652 (82.8%) received the drug during home visits. Among the women who delivered at home, 527 (98.9%) reported taking misoprostol. A uterotonic for PPH prevention was provided at 342 (86.8%) facility-based deliveries. Total uterotonic coverage was 93.7%. No adverse events were reported.
CONCLUSION: It is feasible to achieve high coverage of uterotonic use in a low-resource and postconflict setting with few skilled birth attendants through a combination of advance misoprostol distribution and AMTSL at facilities. Advance distribution through home visits was key to achieving high coverage of misoprostol use.
Copyright © 2014 International Federation of Gynecology and Obstetrics. All rights reserved.

Entities:  

Keywords:  Active management of the third stage of labor; Advance distribution; Community health workers; Coverage; Home birth; Misoprostol; Postpartum hemorrhage prevention; Safety

Mesh:

Substances:

Year:  2014        PMID: 25051905     DOI: 10.1016/j.ijgo.2014.05.016

Source DB:  PubMed          Journal:  Int J Gynaecol Obstet        ISSN: 0020-7292            Impact factor:   3.561


  12 in total

Review 1.  Advance misoprostol distribution to pregnant women for preventing and treating postpartum haemorrhage.

Authors:  Olufemi T Oladapo; Jennifer Blum; Edgardo Abalos; Babasola O Okusanya
Journal:  Cochrane Database Syst Rev       Date:  2020-06-23

2.  The MamaMiso study of self-administered misoprostol to prevent bleeding after childbirth in rural Uganda: a community-based, placebo-controlled randomised trial.

Authors:  Andrew D Weeks; James Ditai; Sam Ononge; Brian Faragher; Laura J Frye; Jill Durocher; Florence M Mirembe; Josaphat Byamugisha; Beverly Winikoff; Zarko Alfirevic
Journal:  BMC Pregnancy Childbirth       Date:  2015-09-14       Impact factor: 3.007

3.  Postpartum hemorrhage prevention in Nepal: a program assessment.

Authors:  Swaraj Pradhan Rajbhandari; Kamal Aryal; Wendy R Sheldon; Bharat Ban; Senendra Raj Upreti; Kiran Regmi; Shilu Aryal; Beverly Winikoff
Journal:  BMC Pregnancy Childbirth       Date:  2017-06-05       Impact factor: 3.007

Review 4.  Task shifting in active management of the third stage of labor: a systematic review.

Authors:  Tessa M Raams; Joyce L Browne; Verena J M M Festen-Schrier; Kerstin Klipstein-Grobusch; Marcus J Rijken
Journal:  BMC Pregnancy Childbirth       Date:  2018-02-06       Impact factor: 3.007

5.  Misoprostol for the prevention of postpartum hemorrhage during home births in rural Lao PDR: establishing a pilot program for community distribution.

Authors:  Jo Durham; Alongkone Phengsavanh; Vanphanom Sychareun; Isaac Hose; Viengnakhone Vongxay; Douangphachanh Xaysomphou; Keith Rickart
Journal:  Int J Womens Health       Date:  2018-05-09

6.  Effectiveness and safety of misoprostol distributed to antenatal women to prevent postpartum haemorrhage after child-births: a stepped-wedge cluster-randomized trial.

Authors:  Sam Ononge; Oona M R Campbell; Frank Kaharuza; James J Lewis; Katherine Fielding; Florence Mirembe
Journal:  BMC Pregnancy Childbirth       Date:  2015-11-26       Impact factor: 3.007

7.  Misoprostol for Prevention of Postpartum Hemorrhage at Home Birth in Afghanistan: Program Expansion Experience.

Authors:  Jaime Haver; Nasratullah Ansari; Partamin Zainullah; Young-Mi Kim; Hannah Tappis
Journal:  J Midwifery Womens Health       Date:  2016-02-05       Impact factor: 2.388

8.  Excessive bleeding is a normal cleansing process: a qualitative study of postpartum haemorrhage among rural Uganda women.

Authors:  Sam Ononge; Elialilia Sarikiaeli Okello; Florence Mirembe
Journal:  BMC Pregnancy Childbirth       Date:  2016-08-08       Impact factor: 3.007

9.  Achieving community-based postpartum follow up in eastern Uganda: the field experience from the MamaMiso Study on antenatal distribution of misoprostol.

Authors:  James Ditai; Laura J Frye; Jill Durocher; Meagan E Byrne; Sam Ononge; Beverly Winikoff; Andrew D Weeks
Journal:  BMC Res Notes       Date:  2017-10-26

10.  Implementation of community based advance distribution of misoprostol in Himachal Pradesh (India): lessons and way forward.

Authors:  Rakesh Parashar; Anadi Gupt; Devina Bajpayee; Anil Gupta; Rohan Thakur; Ankur Sangwan; Anuradha Sharma; Deshraj Sharma; Sachin Gupta; Dinesh Baswal; Gunjan Taneja; Rajeev Gera
Journal:  BMC Pregnancy Childbirth       Date:  2018-10-29       Impact factor: 3.007

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