Literature DB >> 25051403

Modular design, application architecture, and usage of a self-service model for enterprise data delivery: the Duke Enterprise Data Unified Content Explorer (DEDUCE).

Monica M Horvath1, Shelley A Rusincovitch2, Stephanie Brinson3, Howard C Shang4, Steve Evans3, Jeffrey M Ferranti5.   

Abstract

PURPOSE: Data generated in the care of patients are widely used to support clinical research and quality improvement, which has hastened the development of self-service query tools. User interface design for such tools, execution of query activity, and underlying application architecture have not been widely reported, and existing tools reflect a wide heterogeneity of methods and technical frameworks. We describe the design, application architecture, and use of a self-service model for enterprise data delivery within Duke Medicine.
METHODS: Our query platform, the Duke Enterprise Data Unified Content Explorer (DEDUCE), supports enhanced data exploration, cohort identification, and data extraction from our enterprise data warehouse (EDW) using a series of modular environments that interact with a central keystone module, Cohort Manager (CM). A data-driven application architecture is implemented through three components: an application data dictionary, the concept of "smart dimensions", and dynamically-generated user interfaces.
RESULTS: DEDUCE CM allows flexible hierarchies of EDW queries within a grid-like workspace. A cohort "join" functionality allows switching between filters based on criteria occurring within or across patient encounters. To date, 674 users have been trained and activated in DEDUCE, and logon activity shows a steady increase, with variability between months. A comparison of filter conditions and export criteria shows that these activities have different patterns of usage across subject areas.
CONCLUSIONS: Organizations with sophisticated EDWs may find that users benefit from development of advanced query functionality, complimentary to the user interfaces and infrastructure used in other well-published models. Driven by its EDW context, the DEDUCE application architecture was also designed to be responsive to source data and to allow modification through alterations in metadata rather than programming, allowing an agile response to source system changes.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Application development; Cohort definition; Information systems; Medical informatics applications; Research query tool; System design and architecture

Mesh:

Year:  2014        PMID: 25051403      PMCID: PMC4335712          DOI: 10.1016/j.jbi.2014.07.006

Source DB:  PubMed          Journal:  J Biomed Inform        ISSN: 1532-0464            Impact factor:   6.317


  23 in total

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Authors:  Isaac S Kohane; Susanne E Churchill; Shawn N Murphy
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3.  A database de-identification framework to enable direct queries on medical data for secondary use.

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Journal:  Health Informatics J       Date:  2009-06       Impact factor: 2.681

5.  The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories.

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Authors:  Rachel E Behrman; Joshua S Benner; Jeffrey S Brown; Mark McClellan; Janet Woodcock; Richard Platt
Journal:  N Engl J Med       Date:  2011-01-12       Impact factor: 91.245

9.  Calculating the benefits of a Research Patient Data Repository.

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Authors:  Nicholas Anderson; Aaron Abend; Aaron Mandel; Estella Geraghty; Davera Gabriel; Rob Wynden; Michael Kamerick; Kent Anderson; Julie Rainwater; Peter Tarczy-Hornoch
Journal:  J Am Med Inform Assoc       Date:  2011-08-26       Impact factor: 4.497

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  29 in total

Review 1.  Review and evaluation of electronic health records-driven phenotype algorithm authoring tools for clinical and translational research.

Authors:  Jie Xu; Luke V Rasmussen; Pamela L Shaw; Guoqian Jiang; Richard C Kiefer; Huan Mo; Jennifer A Pacheco; Peter Speltz; Qian Zhu; Joshua C Denny; Jyotishman Pathak; William K Thompson; Enid Montague
Journal:  J Am Med Inform Assoc       Date:  2015-07-29       Impact factor: 4.497

2.  Design and Implementation of a Comprehensive Surveillance System for Venous Thromboembolism in a Defined Region Using Electronic and Manual Approaches.

Authors:  Thomas L Ortel; Katie Arnold; Michele Beckman; Audrey Brown; Nimia Reyes; Ibrahim Saber; Ryan Schulteis; Bhavana Pendurthi Singh; Andrea Sitlinger; Elizabeth H Thames
Journal:  Appl Clin Inform       Date:  2019-07-31       Impact factor: 2.342

3.  Design and Implementation of a Secure Computing Environment for Analysis of Sensitive Data at an Academic Medical Center.

Authors:  Peter R Oxley; John Ruffing; Thomas R Campion; Terrie R Wheeler; Curtis L Cole
Journal:  AMIA Annu Symp Proc       Date:  2018-12-05

Review 4.  Electronic Health Records: Then, Now, and in the Future.

Authors:  R S Evans
Journal:  Yearb Med Inform       Date:  2016-05-20

5.  Substance use and mental diagnoses among adults with and without type 2 diabetes: Results from electronic health records data.

Authors:  Li-Tzy Wu; Udi E Ghitza; Bryan C Batch; Michael J Pencina; Leoncio Flavio Rojas; Benjamin A Goldstein; Tony Schibler; Ashley A Dunham; Shelley Rusincovitch; Kathleen T Brady
Journal:  Drug Alcohol Depend       Date:  2015-09-12       Impact factor: 4.492

6.  Infections after kidney transplantation. Does age matter?

Authors:  Marion Hemmersbach-Miller; Barbara D Alexander; Debra L Sudan; Carl Pieper; Kenneth E Schmader
Journal:  Clin Transplant       Date:  2019-03-28       Impact factor: 2.863

Review 7.  Twenty-eight cases of Mycobacterium marinum infection: retrospective case series and literature review.

Authors:  Matthew G Johnson; Jason E Stout
Journal:  Infection       Date:  2015-04-14       Impact factor: 3.553

8.  Nocardia infections in the transplanted host.

Authors:  Marion Hemmersbach-Miller; Jason E Stout; Michael H Woodworth; Gary M Cox; Jennifer L Saullo
Journal:  Transpl Infect Dis       Date:  2018-05-07       Impact factor: 2.228

9.  Pulmonary Hypertension Subtypes and Mortality in CKD.

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Journal:  Am J Kidney Dis       Date:  2019-11-12       Impact factor: 8.860

10.  Single-center analysis of infectious complications in older adults during the first year after kidney transplantation.

Authors:  Marion Hemmersbach-Miller; Barbara D Alexander; Debra L Sudan; Carl Pieper; Kenneth E Schmader
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2018-10-23       Impact factor: 3.267

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