| Literature DB >> 25048817 |
Eric P F Chow1, Glenda Fehler2, Marcus Y Chen1, Catriona S Bradshaw1, Ian Denham2, Matthew G Law3, Christopher K Fairley1.
Abstract
BACKGROUND: The frequency of testing sex workers for sexually transmitted infections (STIs) in Victoria, Australia, was changed from monthly to quarterly on 6 October 2012. Our aim was to determine the impact of this change to the clients seen at the Melbourne Sexual Health Centre (MHSC).Entities:
Mesh:
Year: 2014 PMID: 25048817 PMCID: PMC4105494 DOI: 10.1371/journal.pone.0103081
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Comparison of the number of consultations and consultation hours spent among different risk categories of clients at the MSHC in the monthly and quarterly testing period.
| Clients risk group | Number of consultations | Consultation hours spent | ||||
| Monthly testingperiod N (%) | Quarterly testingperiod N (%) | P-value | Monthly testingperiod Hour (%) | Quarterly testingperiod Hour (%) | P-value | |
|
| 36260 (100%) | 34775 (100%) | – | 10020 (100%) | 9962 (100%) | – |
|
| 7309 (20.2%) | 8571 (24.6%) | <0.001 | 2017 (20.1%) | 2409 (24.2%) | <0.001 |
|
| 9508 (26.2%) | 9827 (28.3%) | <0.001 | 2508 (25.0%) | 2593 (26.0%) | 0.11 |
|
| 6146 (16.9%) | 3453 (9.9%) | <0.001 | 1942 (19.4%) | 1153 (11.6%) | <0.001 |
|
| 13100 (36.1%) | 12724 (36.6%) | 0.20 | 3496 (34.9%) | 3749 (37.6%) | <0.001 |
|
| 711 (2.0%) | 500 (1.7%) | <0.001 | 201 (2.0%) | 155 (1.6%) | 0.016 |
*p<0.05;
**p<0.01;
***p<0.001.
Comparison of the number of consultations with symptomatic conditions among different risk categories of clients at the MSHC in the monthly and quarterly testing period.
| Clients risk group | Number of consultations with symptomatic conditions | Consultation hours spent on symptomatic conditions | ||||
| Monthly testingperiod (N = 36260)N (%) | Quarterly testingperiod (N = 34775)N (%) | P-value | Monthly testingperiod (10020 h)Hour (%) | Quarterly testingperiod (9962 h)Hour (%) | P-value | |
|
| 9838 (27.1%) | 11030 (31.7%) | <0.001 | 3357 (33.5%) | 3704 (37.2%) | <0.001 |
|
| 2662 (7.3%) | 3217 (8.9%) | <0.001 | 861 (8.6%) | 1066 (10.7%) | <0.001 |
|
| 3355 (9.3%) | 3601 (9.9%) | <0.001 | 1174 (11.7%) | 1215 (12.2%) | 0.98 |
|
| 947 (2.6%) | 796 (2.2%) | 0.0055 | 335 (3.3%) | 262 (2.6%) | 0.0031 |
|
| 2834 (7.8%) | 3372 (9.3%) | <0.001 | 972 (9.8%) | 1147 (11.5%) | <0.001 |
|
| 169 (0.5%) | 158 (0.4%) | 0.82 | 59 (0.6%) | 57 (0.6%) | 0.88 |
*p<0.05;
**p<0.01;
***p<0.001.
Comparison of number of diagnosed STI cases among different categories of clients at the MSHC in the monthly and quarterly testing period.
| STIs | Monthly/Quarterly testing period | |||||
| All clients | Heterosexualfemales | Heterosexualmales∧ | Female sexworkers | Men who havesex with men | Male sexworkers | |
|
| 1354 (5.8%)/1562 (6.7%) | 305 (6.7%)/393 (7.0%) | 464 (7.7%)/496 (7.6%) | 91 (1.5%)/64 (1.9%) | 492 (7.4%)/599 (7.9%) | 19 (4.4%)/28 (8.2%) |
|
| 504 (3.1%)/635 (4.3%) | 13 (0.5%)/12 (0.4%) | 55 (5.5%)/64 (6.7%) | 22 (0.4%)/8 (0.2%) | 410 (6.1%)/548 (7.1%) | 21 (5.1%)/31 (10.1%) |
|
| 173 (7.3%)/197 (5.9%) | 30 (6.1%)/39 (5.8%) | 78 (6.1%)/85 (6.0%) | 5 (3.6%)/13 (8.7%) | 60 (6.6%)/60 (5.4%) | 5 (8.9%)/3 (6.1%) |
|
| 135 (0.9%)/122 (0.7%) | 0 (0%)/0 (0%) | 9 (0.2%)/10 (0.3%) | 4 (0.1%)/0 (0%) | 120 (1.9%)/112 (1.5%) | 8 (2.1%)/3 (0.9%) |
|
| 13 (0.2%)/16 (0.5%) | 5 (0.2%)/11 (0.5%) | 0 (0%)/0 (0%) | 8 (0.1%)/5 (0.4%) | 0 (0%)/0 (0%) | 0 (0%)/0 (0%) |
|
| 64 (0.4%)/57 (0.3%) | 0 (0%)/0 (0%) | 3 (0.1%)/1 (0.03%) | 0 (0%)/0 (0%) | 60 (1.0%)/55 (0.8%) | 3 (0.9%)/0 (0%) |
|
| 2243/2589 | 353/455 | 609/656 | 130/90 | 1142/1374 | 56/65 |
Note: The numbers represent the number of positive cases detected, and the bracketed percentages represent the prevalence of infection in the population (i.e. number of positive cases divided by number of laboratory tests ordered).
*p<0.05;
**p<0.01;
***p<0.001.
Fisher’s exact test.
∧Heterosexual men (males) are only tested for gonorrhoea when they have symptoms because gonorrhoea is rare in heterosexual men. Only 936 heterosexual men were tested for gonorrhoea in the monthly and 875 tested in the quarterly period.
There was large number of repeated swab tests performed (i.e. chlamydia, gonorrhoea, M genitalium and trichomonas) in FSW due to the sex work regulation. The prevalence of FSW was adjusted to number of infected FSW individuals divided by the number of FSW individuals tested at least once in the period. The adjusted prevalence of chlamydia in FSW was: 81 (5.1%)/59 (4.0%) [p = 0.16]; gonorrhoea: 22 (1.4%)/8 (0.6%) [p = 0.020]; M genitalium: 5 (4.5%)/9 (8.0%) [p = 0.28]; and trichomonas: 7 (0.4%)/5 (0.6%) [p = 0.61].
Comparison of the detection rates for selected STI among different categories of clients at the MSHC in the monthly and quarterly testing period.
| STI rate/100 consultations (95% CI) | STI rate/100 h (95% CI) | |||||
| Clients risk group | Monthly testingperiod | Quarterly testingperiod | P-value | Monthly testingperiod | Quarterly testingperiod | P-value |
|
| 6.2 (6.0, 6.4) | 7.4 (7.2, 7.7) | <0.001 | 22.4 (21.6, 23.2) | 26.0 (25.1, 26.9) | <0.001 |
|
| 4.8 (4.4, 5.4) | 5.3 (4.9, 5.8) | 0.09 | 17.5 (15.9, 19.2) | 18.9 (17.4, 20.5) | 0.14 |
|
| 6.4 (5.9, 6.9) | 6.7 (6.2, 7.2) | 0.23 | 24.3 (22.6, 26.0) | 25.3 (23.7, 27.0) | 0.23 |
|
| 2.1 (1.8, 2.5) | 2.6 (2.1, 3.2) | 0.065 | 6.7 (5.7, 7.9) | 7.8 (6.4, 9.5) | 0.13 |
|
| 8.7 (8.3, 9.2) | 10.8 (10.3, 11.4) | <0.001 | 32.7 (31.1, 34.2) | 36.6 (35.1, 38.2) | 0.002 |
|
| 7.9 (6.1, 10.1) | 13.0 (10.3, 16.2) | 0.003 | 27.8 (22.1, 34.4) | 43.1 (34.5, 49.8) | 0.013 |
*p<0.05;
**p<0.01;
***p<0.001.
Comparison between the costs associated with female sex workers before and after the change of testing frequency.
| Items | Unit costs (AU$) | Monthly testing period | Quarterly testing period | Sources | ||
| No. of units | Total (AU$) | No. of units | Total (AU$) | |||
| Swab test for chlamydia | 21.50 | 5,964 | 128,226.00 | 3,299 | 70,928.50 | MBS Item 69316 |
| Swab test for gonorrhoea and/or trichomonas | 25.35 | 5,984 | 151,694.40 | 3,228 | 81,829.80 | MBS Item 69312 |
| Screening test for HIV and syphilis | 36.00 | 2,928 | 105,408.00 | 2,973 | 107,028.00 | MBS Item 69390 |
| Screening test for syphilis | 24.65 | 13 | 320.45 | 15 | 369.75 | MBS Item 69387 |
| Screening test for HIV | 13.35 | 7 | 93.45 | 11 | 146.85 | MBS Item 69384 |
| Clinical consultation (Level B) | 36.30 | 2,814 | 102,148.20 | 1,178 | 42,761.40 | MBS Item 23 |
| Clinical consultation (Level C) | 70.30 | 2,616 | 183,904.80 | 1,729 | 121,548.70 | MBS Item 36 |
| TOTAL | 671,795.30 | 426,613.00 | ||||
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