Literature DB >> 25048759

The content of attenuated psychotic symptoms in those at clinical high risk for psychosis.

Catherine Marshall1, Erin Denny1, Kristin S Cadenhead2, Tyrone D Cannon3, Barbara A Cornblatt4, Thomas H McGlashan5, Diana O Perkins6, Larry J Seidman7, Ming T Tsuang8, Scott W Woods5, Elaine Walker9, Jean Addington10.   

Abstract

Recent research has started to focus on identifying individuals who are at clinical high risk of developing psychosis as a means to try and understand the predictors and mechanisms involved in the progress to a full psychotic episode. The aim of the current study was to provide an initial description and prevalence rates of specific content found within attenuated positive symptoms. The Content of Attenuated Positive Symptoms (CAPS) codebook was used by independent raters to determine the presence of content within a sample of written vignettes. Krippendorff's alpha was used to determine inter-rater reliability. Overall, the majority of items fell in or above an acceptable range of reliability. There was heterogeneity present in the types of content endorsed. However, the most commonly endorsed items included being perplexed by reality, increased hypervigilence, being gifted, hearing indistinct and distinct sounds, seeing figures or shadows, something touching the individual, and unpleasant smells. The use of the CAPS codebook is a reliable way to code the content of attenuated positive symptoms. Identifying and monitoring the presence of certain content may provide insight into the presence of other comorbid issues and the potential for future conversion.
Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Clinical high risk; Content analysis; Positive symptoms; Psychotic disorders

Mesh:

Year:  2014        PMID: 25048759      PMCID: PMC4356487          DOI: 10.1016/j.psychres.2014.06.023

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN: 0165-1781            Impact factor:   3.222


  16 in total

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Review 6.  Monitoring and care of young people at incipient risk of psychosis.

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2.  Distinct Relationships Between Visual and Auditory Perceptual Abnormalities and Conversion to Psychosis in a Clinical High-Risk Population.

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5.  Perceptual abnormalities in clinical high risk youth and the role of trauma, cannabis use and anxiety.

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6.  The Violent Content in Attenuated Psychotic Symptoms.

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7.  An imaging-based risk calculator for prediction of conversion to psychosis in clinical high-risk individuals using glutamate 1H MRS.

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