Literature DB >> 25048036

Reproductive endocrinology: functional effects of sex hormone-binding globulin variants.

Michaël R Laurent1, Dirk Vanderschueren2.   

Abstract

A new study has found eight single nucleotide polymorphisms in sex hormone-binding globulin that functionally affect its affinity for androgens or estrogens and other biochemical properties. This finding adds to growing concern about the ‘one size fits all’ approach in formulas to calculate free or bioavailable concentrations of estradiol and testosterone.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 25048036     DOI： 10.1038/nrendo.2014.120

Source DB:  PubMed          Journal:  Nat Rev Endocrinol        ISSN： 1759-5029            Impact factor:   43.330


  10 in total

1.  A critical evaluation of simple methods for the estimation of free testosterone in serum.

Authors:  A Vermeulen; L Verdonck; J M Kaufman
Journal:  J Clin Endocrinol Metab       Date:  1999-10       Impact factor: 5.958

2.  Editorial: Sex hormone binding globulin: inhibitor or facilitator (or both) of sex steroid action?

Authors:  Sundeep Khosla
Journal:  J Clin Endocrinol Metab       Date:  2006-12       Impact factor: 5.958

Review 3.  Evolving utility of sex hormone-binding globulin measurements in clinical medicine.

Authors:  Geoffrey L Hammond; Tsung-Sheng Wu; Marc Simard
Journal:  Curr Opin Endocrinol Diabetes Obes       Date:  2012-06       Impact factor: 3.243

Review 4.  All sex steroids are made intracellularly in peripheral tissues by the mechanisms of intracrinology after menopause.

Authors:  Fernand Labrie
Journal:  J Steroid Biochem Mol Biol       Date:  2014-06-09       Impact factor: 4.292

5.  Serum levels of sex hormone-binding globulin (SHBG) are not associated with lower levels of non-SHBG-bound testosterone in male newborns and healthy adult men.

Authors:  Willem de Ronde; Yvonne T van der Schouw; Frank H Pierik; Huibert A P Pols; Majon Muller; Diederick E Grobbee; Louis J G Gooren; Rob F A Weber; Frank H de Jong
Journal:  Clin Endocrinol (Oxf)       Date:  2005-04       Impact factor: 3.478

6.  Human sex hormone-binding globulin variants associated with hyperandrogenism and ovarian dysfunction.

Authors:  Kevin N Hogeveen; Patrice Cousin; Michel Pugeat; Didier Dewailly; Benoît Soudan; Geoffrey L Hammond
Journal:  J Clin Invest       Date:  2002-04       Impact factor: 14.808

7.  Position statement: Utility, limitations, and pitfalls in measuring testosterone: an Endocrine Society position statement.

Authors:  William Rosner; Richard J Auchus; Ricardo Azziz; Patrick M Sluss; Hershel Raff
Journal:  J Clin Endocrinol Metab       Date:  2006-11-07       Impact factor: 5.958

8.  Sex hormone binding globulin deficiency due to a homozygous missense mutation.

Authors:  M J Vos; G S Mijnhout; J M M Rondeel; W Baron; P H P Groeneveld
Journal:  J Clin Endocrinol Metab       Date:  2014-06-17       Impact factor: 5.958

9.  Naturally occurring mutants inform SHBG structure and function.

Authors:  Tsung-Sheng Wu; Geoffrey L Hammond
Journal:  Mol Endocrinol       Date:  2014-06-03

10.  Genetic determinants of serum testosterone concentrations in men.

Authors:  Claes Ohlsson; Henri Wallaschofski; Kathryn L Lunetta; Lisette Stolk; John R B Perry; Annemarie Koster; Ann-Kristin Petersen; Joel Eriksson; Terho Lehtimäki; Ilpo T Huhtaniemi; Geoffrey L Hammond; Marcello Maggio; Andrea D Coviello; Luigi Ferrucci; Margit Heier; Albert Hofman; Kate L Holliday; John-Olov Jansson; Mika Kähönen; David Karasik; Magnus K Karlsson; Douglas P Kiel; Yongmei Liu; Osten Ljunggren; Mattias Lorentzon; Leo-Pekka Lyytikäinen; Thomas Meitinger; Dan Mellström; David Melzer; Iva Miljkovic; Matthias Nauck; Maria Nilsson; Brenda Penninx; Stephen R Pye; Ramachandran S Vasan; Martin Reincke; Fernando Rivadeneira; Abdelouahid Tajar; Alexander Teumer; André G Uitterlinden; Jagadish Ulloor; Jorma Viikari; Uwe Völker; Henry Völzke; H Erich Wichmann; Tsung-Sheng Wu; Wei Vivian Zhuang; Elad Ziv; Frederick C W Wu; Olli Raitakari; Anna Eriksson; Martin Bidlingmaier; Tamara B Harris; Anna Murray; Frank H de Jong; Joanne M Murabito; Shalender Bhasin; Liesbeth Vandenput; Robin Haring
Journal:  PLoS Genet       Date:  2011-10-06       Impact factor: 5.917
  10 in total
  12 in total

1.  Estrogens, the be-all and end-all of male hypogonadal bone loss?

Authors:  M R Laurent; E Gielen; D Vanderschueren
Journal:  Osteoporos Int       Date:  2014-11-07       Impact factor: 4.507

2.  Sex differences in the estrogen-dependent regulation of temporomandibular joint remodeling in altered loading.

Authors:  J L Robinson; K Cass; R Aronson; T Choi; M Xu; R Buttenbaum; H Drissi; H H Lu; J Chen; S Wadhwa
Journal:  Osteoarthritis Cartilage       Date:  2016-11-27       Impact factor: 6.576

Review 3.  Estrogens and Androgens in Skeletal Physiology and Pathophysiology.

Authors:  Maria Almeida; Michaël R Laurent; Vanessa Dubois; Frank Claessens; Charles A O'Brien; Roger Bouillon; Dirk Vanderschueren; Stavros C Manolagas
Journal:  Physiol Rev       Date:  2017-01       Impact factor: 37.312

4.  Erectile Dysfunction and Low Sex Drive in Men with Type 2 DM: The Potential Role of Diabetic Pharmacotherapy.

Authors:  Hayder M Al-Kuraishy; Ali I Al-Gareeb
Journal:  J Clin Diagn Res       Date:  2016-12-01

5.  Sex hormones, sex hormone binding globulin, and vertebral fractures in older men.

Authors:  Peggy M Cawthon; John T Schousboe; Stephanie L Harrison; Kristine E Ensrud; Dennis Black; Jane A Cauley; Steven R Cummings; Erin S LeBlanc; Gail A Laughlin; Carrie M Nielson; Augusta Broughton; Deborah M Kado; Andrew R Hoffman; Sophie A Jamal; Elizabeth Barrett-Connor; Eric S Orwoll
Journal:  Bone       Date:  2016-01-08       Impact factor: 4.398

Review 6.  Sex steroid actions in male bone.

Authors:  Dirk Vanderschueren; Michaël R Laurent; Frank Claessens; Evelien Gielen; Marie K Lagerquist; Liesbeth Vandenput; Anna E Börjesson; Claes Ohlsson
Journal:  Endocr Rev       Date:  2014-09-09       Impact factor: 19.871

7.  Human sex hormone-binding globulin as a potential target of alternate plasticizers: an in silico study.

Authors:  Ishfaq A Sheikh; Muhammad Yasir; Muhammad Abu-Elmagd; Tanveer A Dar; Adel M Abuzenadah; Ghazi A Damanhouri; Mohammed Al-Qahtani; Mohd A Beg
Journal:  BMC Struct Biol       Date:  2016-09-30

8.  Allosterically Coupled Multisite Binding of Testosterone to Human Serum Albumin.

Authors:  Abhilash Jayaraj; Heidi A Schwanz; Daniel J Spencer; Shalender Bhasin; James A Hamilton; B Jayaram; Anna L Goldman; Meenakshi Krishna; Maya Krishnan; Aashay Shah; Zhendong Jin; Eileen Krenzel; Sashi N Nair; Sid Ramesh; Wen Guo; Gerhard Wagner; Haribabu Arthanari; Liming Peng; Brian Lawney; Ravi Jasuja
Journal:  Endocrinology       Date:  2021-02-01       Impact factor: 4.736

9.  Estradiol induces allosteric coupling and partitioning of sex-hormone-binding globulin monomers among conformational states.

Authors:  Ravi Jasuja; Daniel Spencer; Abhilash Jayaraj; Liming Peng; Meenakshi Krishna; Brian Lawney; Priyank Patel; Bhyravabhotla Jayaram; Kelly M Thayer; David L Beveridge; Shalender Bhasin
Journal:  iScience       Date:  2021-04-09

10.  Effects of sulfonylurea as initial treatment on testosterone of middle-aged men with type 2 diabetes: A 16-week, pilot study.

Authors:  Long Wong; Hong-Mei Chen; Shui-Qing Lai; Hua-Zhang Yang; Jian Kuang; Jian-Hao Pei
Journal:  J Diabetes Investig       Date:  2015-01-16       Impact factor: 4.232
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.