Aimé Bonny1, Dominique Noah Noah2, Marcus Ngantcha3, Robinson Ateh4, Cécile Saka5, Jonas Wa6, Réné Fonga7, Sylvie Ndongo Amougou8, Bo Gregers Winkel9, Pier Lambiase10, Silvia G Priori11. 1. Department of Internal Medicine, University Hospital Laquintinie and Faculty of Medicine, Douala, Cameroon; Laboratoire d'explorations cardiovasculaires, service de cardiologie, hôpital Laquintinie de Douala, Douala, Cameroon. Electronic address: aimebonny@yahoo.fr. 2. Service de gastroenterologie, hôpital Central, Yaoundé, Cameroon. 3. Biostatistic, Statprest, Paris, France. 4. Department of Internal Medicine, University Hospital Laquintinie and Faculty of Medicine, Douala, Cameroon. 5. Laboratoire d'explorations cardiovasculaires, service de cardiologie, hôpital Laquintinie de Douala, Douala, Cameroon. 6. Service de médicine, hôpital de district de Bonassama, Douala, Cameroon. 7. Department of Internal Medicine and Mortuary Ward, District Hospital of New-Bell, Douala, Cameroon. 8. Service de réanimation, centre hospitalier universitaire de Yaoundé, Yaoundé, Cameroon. 9. Department of Cardiology, Laboratory for Molecular Cardiology, Rigs hospital, University Hospital Copenhagen, Denmark. 10. UCL Institute of Cardiovascular Sciences, University College London, London, UK. 11. Department of Molecular Genetic, Fondazione Salvatore Maugeri, IRCCS, Pavia, Italy; Molecular Medicine Department, University of Pavia, Pavia, Italy.
Abstract
BACKGROUND: The burden of sudden unexplained death in sub-Saharan Africa is unknown. AIM: The aim of this study is to establish the epidemiology of sudden cardiac death in Cameroon. METHODS: The Douala sudden unexplained death (Douala-SUD) study is a prospective, multiple-source, community-based surveillance of all cases of unexpected death (< 24 hours from onset of symptoms) occurring in victims aged>15 years. After approval from institutional boards, all deaths occurring in residents of four areas of Douala city will be checked for circumstances of death and past medical history. Subjects who die naturally will be further investigated. Unexpected death victims will be checked for detailed demographic, clinical, electrocardiographic, echocardiographic and biological records. Autopsy background and genetic analysis (postmortem or in first relatives if the young victim is aged<40 years) will be performed as far as possible. Finally, the use of cardiopulmonary resuscitation efforts during the timeframe of sudden cardiac arrest will also be evaluated. CONCLUSION: The Douala-SUD study will provide comprehensive, contemporary data on the epidemiology of sudden unexplained and cardiac death in sub-Saharan Africa and will help in the development of strategies to prevent and manage cardiac arrest in Cameroon as well as in other sub-Saharan countries.
BACKGROUND: The burden of sudden unexplained death in sub-Saharan Africa is unknown. AIM: The aim of this study is to establish the epidemiology of sudden cardiac death in Cameroon. METHODS: The Douala sudden unexplained death (Douala-SUD) study is a prospective, multiple-source, community-based surveillance of all cases of unexpected death (< 24 hours from onset of symptoms) occurring in victims aged>15 years. After approval from institutional boards, all deaths occurring in residents of four areas of Douala city will be checked for circumstances of death and past medical history. Subjects who die naturally will be further investigated. Unexpected death victims will be checked for detailed demographic, clinical, electrocardiographic, echocardiographic and biological records. Autopsy background and genetic analysis (postmortem or in first relatives if the young victim is aged<40 years) will be performed as far as possible. Finally, the use of cardiopulmonary resuscitation efforts during the timeframe of sudden cardiac arrest will also be evaluated. CONCLUSION: The Douala-SUD study will provide comprehensive, contemporary data on the epidemiology of sudden unexplained and cardiac death in sub-Saharan Africa and will help in the development of strategies to prevent and manage cardiac arrest in Cameroon as well as in other sub-Saharan countries.
Authors: Gladys M K Tchanana; Marcus Ngantcha; Matthew F Yuyun; Olujimi A Ajijola; Samuel Mbouh; Steve C T Tchameni; Ahmed Suliman; Aimé Bonny Journal: BMJ Open Sport Exerc Med Date: 2020-08-23
Authors: Aimé Bonny; Kemi Tibazarwa; Samuel Mbouh; Jonas Wa; Réné Fonga; Cecile Saka; Marcus Ngantcha Journal: Int J Epidemiol Date: 2017-08-01 Impact factor: 7.196
Authors: Elizabeth Davida Paratz; Luke Rowsell; Dominica Zentner; Sarah Parsons; Natalie Morgan; Tina Thompson; Paul James; Andreas Pflaumer; Christopher Semsarian; Karen Smith; Dion Stub; Andre La Gerche Journal: Open Heart Date: 2020-01-20