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Literature DB >> 25047246

Bio-inspired cryo-ink preserves red blood cell phenotype and function during nanoliter vitrification.

Rami El Assal¹, Sinan Guven, Umut Atakan Gurkan, Irep Gozen, Hadi Shafiee, Sedef Dalbeyler, Noor Abdalla, Gawain Thomas, Wendy Fuld, Ben M W Illigens, Jessica Estanislau, Joseph Khoory, Richard Kaufman, Claudia Zylberberg, Neal Lindeman, Qi Wen, Ionita Ghiran, Utkan Demirci.

Abstract

Current red-blood-cell cryopreservation methods utilize bulk volumes, causing cryo-injury of cells, which results in irreversible disruption of cell morphology, mechanics, and function. An innovative approach to preserve human red-blood-cell morphology, mechanics, and function following vitrification in nanoliter volumes is developed using a novel cryo-ink integrated with a bioprinting approach.

Entities: CellLine Chemical Disease Gene Species

Keywords: bio-inspired materials; bio-printing; cryoprotective agents; nanoliter vitrification; red blood cell cryopreservation

Mesh：

Substances：

Year: 2014 PMID： 25047246 PMCID： PMC4161503 DOI： 10.1002/adma.201400941

Source DB: PubMed Journal: Adv Mater ISSN： 0935-9648 Impact factor: 30.849

53 in total

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11 in total

1. Deformation of a single mouse oocyte in a constricted microfluidic channel.

Authors: ZhengYuan Luo; Sinan Guven; Irep Gozen; Pu Chen; Savas Tasoglu; Raymond M Anchan; BoFeng Bai; Utkan Demirci
Journal: Microfluid Nanofluidics Date: 2015-07-29 Impact factor: 2.529

2. Bio-inspired solute enables preservation of human oocytes using minimum volume vitrification.

Authors: Jung Kyu Choi; Rami El Assal; Nicholas Ng; Elizabeth Ginsburg; Richard L Maas; Raymond M Anchan; Utkan Demirci
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4. Highlights from the latest articles in advanced biomanufacturing at micro- and nano-scale.

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Review 5. Cryopreservation of NK and T Cells Without DMSO for Adoptive Cell-Based Immunotherapy.

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Authors: Reinier J de Vries; Peony D Banik; Sonal Nagpal; Lindong Weng; Sinan Ozer; Thomas M van Gulik; Mehmet Toner; Shannon N Tessier; Korkut Uygun
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Authors: Rami El Assal; Umut A Gurkan; Pu Chen; Franceline Juillard; Alessandro Tocchio; Thiruppathiraja Chinnasamy; Chantal Beauchemin; Sebnem Unluisler; Serli Canikyan; Alyssa Holman; Srikar Srivatsa; Kenneth M Kaye; Utkan Demirci
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10. Engineering cancer microenvironments for in vitro 3-D tumor models.

Authors: Waseem Asghar; Rami El Assal; Hadi Shafiee; Sharon Pitteri; Ramasamy Paulmurugan; Utkan Demirci
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