AIM: The aim of our study was to assess the prevalence, risk factors for acquisition and the clinical characteristics of H. pylori infection in Malagasy children. METHODS: A 2 year prospective study was conducted among 434 children from a rural (group A) and an urban area (group B). H. pylori status was evaluated by an ELISA serological test. Various demographic and clinical characteristics were recorded and subjected to statistical analysis. RESULTS: The prevalence of H. pylori infection was 39.6% and increased significantly from 18.1% for children <1 year old to 61.5% for children >10 years old. It was significantly higher in group B (46.9%) than in group A (26.4%). Using multivariate logistic regression modelling, a significant association was found between H. pylori infection and drinking spring water. Exposure to antibiotics during the previous year had no observable effect on H. pylori. CONCLUSION: The overall prevalence of H. pylori infection among Malagasy children was 39.6%. A significant association between H. pylori infection and drinking spring water was found.
AIM: The aim of our study was to assess the prevalence, risk factors for acquisition and the clinical characteristics of H. pyloriinfection in Malagasy children. METHODS: A 2 year prospective study was conducted among 434 children from a rural (group A) and an urban area (group B). H. pylori status was evaluated by an ELISA serological test. Various demographic and clinical characteristics were recorded and subjected to statistical analysis. RESULTS: The prevalence of H. pyloriinfection was 39.6% and increased significantly from 18.1% for children <1 year old to 61.5% for children >10 years old. It was significantly higher in group B (46.9%) than in group A (26.4%). Using multivariate logistic regression modelling, a significant association was found between H. pyloriinfection and drinking spring water. Exposure to antibiotics during the previous year had no observable effect on H. pylori. CONCLUSION: The overall prevalence of H. pyloriinfection among Malagasy children was 39.6%. A significant association between H. pyloriinfection and drinking spring water was found.
Authors: Sabine Kienesberger; Guillermo I Perez-Perez; Asalia Z Olivares; Pradip Bardhan; Shafiqul A Sarker; Kh Zahid Hasan; R Bradley Sack; Martin J Blaser Journal: Gut Microbes Date: 2018-03-01
Authors: Phoebe Aitila; Michael Mutyaba; Simon Okeny; Maurice Ndawula Kasule; Rashid Kasule; Frank Ssedyabane; Benson Okongo; Richard Onyuthi Apecu; Enoch Muwanguzi; Caesar Oyet Journal: J Trop Med Date: 2019-03-07