Literature DB >> 2504662

Interferon-gamma as an adjuvant in immunocompromised mice.

A W Heath1, M E Devey, I N Brown, C E Richards, J H Playfair.   

Abstract

We have compared interferon-gamma (IFN-gamma) with saponin and interleukin-1 (IL-1) as adjuvants for a blood-stage malaria vaccine in mice with various immunological abnormalities. IFN-gamma was particularly effective in Biozzi low antibody responder mice, mice selectively bred to produce antibody of low affinity, and mice depleted of CD4+ T cells. IFN-gamma and other cytokines may be safe adjuvants for use in human immunodeficiency states.

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Year:  1989        PMID： 2504662      PMCID： PMC1385324     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  22 in total

1.  The genetic control of antibody affinity in mice.

Authors:  F E Katz; M W Steward
Journal:  Immunology       Date:  1975-09       Impact factor: 7.397

2.  Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo.

Authors:  S P Cobbold; A Jayasuriya; A Nash; T D Prospero; H Waldmann
Journal:  Nature       Date:  1984 Dec 6-12       Impact factor: 49.962

3.  Macrophage functions in Biozzi mice.

Authors:  H M Dockrell; J Taverne; R Lelchuk; P Depledge; I N Brown; J H Playfair
Journal:  Immunology       Date:  1985-07       Impact factor: 7.397

4.  Rat x rat hybrid myelomas and a monoclonal anti-Fd portion of mouse IgG.

Authors:  G Galfrè; C Milstein; B Wright
Journal:  Nature       Date:  1979-01-11       Impact factor: 49.962

5.  Blood-stage malaria in Biozzi high and low antibody responder mice: the importance of antibody and macrophages in immunity.

Authors:  I N Brown; H M Dockrell; J B de Souza; J H Playfair
Journal:  Ann Immunol (Paris)       Date:  1984 Mar-Apr

6.  The adjuvanticity of interleukin 1 in vivo.

Authors:  M J Staruch; D D Wood
Journal:  J Immunol       Date:  1983-05       Impact factor: 5.422

7.  Antibody affinity maturation in selectively bred high and low-affinity mice.

Authors:  M W Steward; C Stanley; M D Furlong
Journal:  Eur J Immunol       Date:  1986-01       Impact factor: 5.532

8.  Vaccination of mice against malaria with soluble antigens. I. The effect of detergent, route of injection, and adjuvant.

Authors:  J H Playfair; J B De Souza
Journal:  Parasite Immunol       Date:  1986-09       Impact factor: 2.280

9.  Prostaglandin E2 production is enhanced in mice genetically selected to produce high affinity antibody responses.

Authors:  C Phillips
Journal:  Cell Immunol       Date:  1989-04-01       Impact factor: 4.868

10.  Regulation of murine macrophage Ia antigen expression by a lymphokine with immune interferon activity.

Authors:  P S Steeg; R N Moore; H M Johnson; J J Oppenheim
Journal:  J Exp Med       Date:  1982-12-01       Impact factor: 14.307
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  8 in total

1.  Gamma interferon and monophosphoryl lipid A-trehalose dicorynomycolate are efficient adjuvants for Mycobacterium tuberculosis multivalent acellular vaccine.

Authors:  Avi-Hai Hovav; Yolanta Fishman; Herve Bercovier
Journal:  Infect Immun       Date:  2005-01       Impact factor: 3.441

2.  Conjugation of interferon-gamma to antigen enhances its adjuvanticity.

Authors:  A W Heath; J H Playfair
Journal:  Immunology       Date:  1990-11       Impact factor: 7.397

3.  Experimental allergic encephalomyelitis (EAE) in mice selectively bred to produce high affinity (HA) or low affinity (LA) antibody responses.

Authors:  M E Devey; P J Major; K M Bleasdale-Barr; G P Holland; M C Dal Canto; P Y Paterson
Journal:  Immunology       Date:  1990-04       Impact factor: 7.397

4.  Recombinant human migration inhibitory factor has adjuvant activity.

Authors:  W Y Weiser; L M Pozzi; R G Titus; J R David
Journal:  Proc Natl Acad Sci U S A       Date:  1992-09-01       Impact factor: 11.205

5.  Antibody response in Plasmodium vinckei malaria after treatment with chloroquine and adjuvant interferon-gamma.

Authors:  S Finnemann; P G Kremsner; M F Chaves; C Schumacher; S Neifer; U Bienzle
Journal:  Parasitol Res       Date:  1992       Impact factor: 2.289

6.  Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses.

Authors:  Mark Melchers; Ilja Bontjer; Tommy Tong; Nancy P Y Chung; Per Johan Klasse; Dirk Eggink; David C Montefiori; Maurizio Gentile; Andrea Cerutti; William C Olson; Ben Berkhout; James M Binley; John P Moore; Rogier W Sanders
Journal:  J Virol       Date:  2011-12-28       Impact factor: 5.103

7.  Effects of Chicken Interferon Gamma on Newcastle Disease Virus Vaccine Immunogenicity.

Authors:  Stivalis Cardenas-Garcia; Robert P Dunwoody; Valerie Marcano; Diego G Diel; Robert J Williams; Robert M Gogal; Corrie C Brown; Patti J Miller; Claudio L Afonso
Journal:  PLoS One       Date:  2016-07-13       Impact factor: 3.240

Review 8.  Tune Up In Situ Autovaccination against Solid Tumors with Oncolytic Viruses.

Authors:  Teresa Nguyen; Naze G Avci; Dong Ho Shin; Naiara Martinez-Velez; Hong Jiang
Journal:  Cancers (Basel)       Date:  2018-05-31       Impact factor: 6.639
  8 in total

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