M S R G Araújo1, L C Souza1, Fabianni Magalhães Apolonio1, Lívia Oliveira Barros1, Alessandra Reis2, Alessandro Dourado Loguercio2, V P A Saboia3. 1. Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Fortaleza, Ceará, Brazil. 2. Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Ponta Grossa, Paraná, Brazil. 3. Department of Restorative Dentistry, Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Fortaleza, Ceará, Brazil. Electronic address: vpsaboia@yahoo.com.
Abstract
OBJECTIVES: The aim of this 24-month double-blind randomized paired-tooth clinical study was to evaluate the 2-year clinical performance of two self-etch adhesives containing or not chlorhexidine digluconate (CHX) in non-carious cervical lesions (NCCLs). METHODS: Twenty-two patients, with at least four NCCLs, participated in this study. After sample size calculation, 126 restorations were assigned to one of the following groups: CSE--Clearfil SE Bond (Kuraray); CSE/CHX--Clearfil SE Bond+CHX; ADS--AdheSE (Ivoclar Vivadent); and ADS/CHX--AdheSE+CHX. The composite resin Filtek Z-250 composite (3M ESPE) was placed incrementally by one expert operator. The restorations were evaluated at baseline and after 2 years using the modified USPHS criteria. Statistical analyses were performed with Friedman repeated measures ANOVA by rank and Fisher exact test for significance in each pair (α=0.05). RESULTS: No significant difference was observed between baseline and 2-year for any criteria when adhesives with and without the addition of CHX were compared (p>0.05). ADS and ADS/CHX resulted in lower retention rates (82% on average) than CSE and CSE/CHX (97%) (p=0.02). CONCLUSIONS: The inclusion of CHX into the primer of both self-etch systems did not add clinical advantages over the 2-year period. Clearfil SE Bond resulted in better retention rate than AdheSE. CLINICAL SIGNIFICANCE: It is more important to choose a gold standard self-etch adhesive, like a Clearfil SE Bond, than to consider the inclusion of CHX in the self-etch adhesives.
RCT Entities:
OBJECTIVES: The aim of this 24-month double-blind randomized paired-tooth clinical study was to evaluate the 2-year clinical performance of two self-etch adhesives containing or not chlorhexidine digluconate (CHX) in non-carious cervical lesions (NCCLs). METHODS: Twenty-two patients, with at least four NCCLs, participated in this study. After sample size calculation, 126 restorations were assigned to one of the following groups: CSE--Clearfil SE Bond (Kuraray); CSE/CHX--Clearfil SE Bond+CHX; ADS--AdheSE (Ivoclar Vivadent); and ADS/CHX--AdheSE+CHX. The composite resin Filtek Z-250 composite (3M ESPE) was placed incrementally by one expert operator. The restorations were evaluated at baseline and after 2 years using the modified USPHS criteria. Statistical analyses were performed with Friedman repeated measures ANOVA by rank and Fisher exact test for significance in each pair (α=0.05). RESULTS: No significant difference was observed between baseline and 2-year for any criteria when adhesives with and without the addition of CHX were compared (p>0.05). ADS and ADS/CHX resulted in lower retention rates (82% on average) than CSE and CSE/CHX (97%) (p=0.02). CONCLUSIONS: The inclusion of CHX into the primer of both self-etch systems did not add clinical advantages over the 2-year period. Clearfil SE Bond resulted in better retention rate than AdheSE. CLINICAL SIGNIFICANCE: It is more important to choose a gold standard self-etch adhesive, like a Clearfil SE Bond, than to consider the inclusion of CHX in the self-etch adhesives.