Literature DB >> 25046093

The ethics of clinical trials for cancer therapy.

Lynn J Howie1, Jeffrey M Peppercorn2.   

Abstract

Cancer clinical trials are intended to evaluate novel interventions and to improve outcomes. Such research depends on the participation of patients seeking the best options for care. The design, conduct, and analysis of trials must therefore be grounded in an ethical framework that respects and protects the interests of clinical trial participants.

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Year:  2014        PMID： 25046093     DOI： 10.18043/ncm.75.4.270

Source DB:  PubMed          Journal:  N C Med J        ISSN： 0029-2559


  3 in total

1.  Use of real-world evidence in cancer drug funding decisions in Canada: a qualitative study of stakeholders' perspectives.

Authors:  Marc Clausen; Chloe Mighton; Ruhi Kiflen; Agnes Sebastian; Wei Fang Dai; Rebecca E Mercer; Jaclyn M Beca; Wanrudee Isaranuwatchai; Kelvin K W Chan; Yvonne Bombard
Journal:  CMAJ Open       Date:  2020-11-24

2.  Participation in Cancer Pharmacogenomic Studies: A Study of 8456 Patients Registered to Clinical Trials in the Cancer and Leukemia Group B (Alliance).

Authors:  Lynn G Dressler; Allison M Deal; Kouros Owzar; Dorothy Watson; Katherine Donahue; Paula N Friedman; Mark J Ratain; Howard L McLeod
Journal:  J Natl Cancer Inst       Date:  2015-07-09       Impact factor: 13.506

3.  Developing a framework to incorporate real-world evidence in cancer drug funding decisions: the Canadian Real-world Evidence for Value of Cancer Drugs (CanREValue) collaboration.

Authors:  Kelvin Chan; Seungree Nam; Bill Evans; Claire de Oliveira; Alexandra Chambers; Scott Gavura; Jeffrey Hoch; Rebecca E Mercer; Wei Fang Dai; Jaclyn Beca; Mina Tadrous; Wanrudee Isaranuwatchai
Journal:  BMJ Open       Date:  2020-01-07       Impact factor: 2.692
  3 in total

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