Literature DB >> 2504153

Genomic structure of murine beta-1,4-galactosyltransferase.

G F Hollis1, J G Douglas, N L Shaper, J H Shaper, J M Stafford-Hollis, R J Evans, I R Kirsch.   

Abstract

We have isolated a series of overlapping murine genomic DNA clones that include the complete coding sequence of the Golgi membrane bound marker enzyme beta-1,4-galactosyltransferase. The coding sequence is distributed into six exons spanning 50,000 b.p. of mouse chromosome 4. The COOH terminal domain is predominantly encoded by exons 2-6 and the transmembrane and amino terminal cytoplasmic domains are encoded by exon 1. S1 analysis establishes the most 5' transcriptional initiation site 190 b.p. upstream of the first methionine residue.

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Year:  1989        PMID： 2504153     DOI： 10.1016/0006-291x(89)90782-1

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  10 in total

Review 1.  Beta1,4-galactosyltransferase and lactose biosynthesis: recruitment of a housekeeping gene from the nonmammalian vertebrate gene pool for a mammary gland specific function.

Authors:  N L Shaper; M Charron; N W Lo; J H Shaper
Journal:  J Mammary Gland Biol Neoplasia       Date:  1998-07       Impact factor: 2.673

2.  Second Jenner international glycoimmunology meeting.

Authors: 
Journal:  Ann Rheum Dis       Date:  1992-11       Impact factor: 19.103

3.  Knockout of mouse beta 1,4-galactosyltransferase-1 gene results in a dramatic shift of outer chain moieties of N-glycans from type 2 to type 1 chains in hepatic membrane and plasma glycoproteins.

Authors:  N Kotani; M Asano; Y Iwakura; S Takasaki
Journal:  Biochem J       Date:  2001-08-01       Impact factor: 3.857

4.  Murine beta 1,4-galactosyltransferase: both the amounts and structure of the mRNA are regulated during spermatogenesis.

Authors:  N L Shaper; W W Wright; J H Shaper
Journal:  Proc Natl Acad Sci U S A       Date:  1990-01       Impact factor: 11.205

5.  Isolation and characterization of a pseudogene related to human core 2 beta-1,6-N-acetylglucosaminyl-transferase.

Authors:  M F Bierhuizen; K Maemura; M Fukuda
Journal:  Glycoconj J       Date:  1995-12       Impact factor: 2.916

6.  Functional domains of bovine beta-1,4 galactosyltransferase.

Authors:  E E Boeggeman; P V Balaji; P K Qasba
Journal:  Glycoconj J       Date:  1995-12       Impact factor: 2.916

7.  Biosynthesis in vitro of neolactotetraosylceramide by a galactosyltransferase from mouse T-lymphoma: purification and kinetic studies; synthesis of neolacto and polylactosamine core.

Authors:  M Basu; S A Weng; H Tang; F Khan; F Rossi; S Basu
Journal:  Glycoconj J       Date:  1996-06       Impact factor: 2.916

8.  Growth retardation and early death of beta-1,4-galactosyltransferase knockout mice with augmented proliferation and abnormal differentiation of epithelial cells.

Authors:  M Asano; K Furukawa; M Kido; S Matsumoto; Y Umesaki; N Kochibe; Y Iwakura
Journal:  EMBO J       Date:  1997-04-15       Impact factor: 11.598

9.  Agalactosyl IgG and beta-1,4-galactosyltransferase gene expression in rheumatoid arthritis patients and in the arthritis-prone MRL lpr/lpr mouse.

Authors:  P A Jeddi; K B Bodman-Smith; T Lund; P M Lydyard; L Mengle-Gaw; D A Isenberg; P Youinou; P J Delves
Journal:  Immunology       Date:  1996-04       Impact factor: 7.397

10.  Molecular cloning and expression of cDNA encoding the enzyme that controls conversion of high-mannose to hybrid and complex N-glycans: UDP-N-acetylglucosamine: alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.

Authors:  M Sarkar; E Hull; Y Nishikawa; R J Simpson; R L Moritz; R Dunn; H Schachter
Journal:  Proc Natl Acad Sci U S A       Date:  1991-01-01       Impact factor: 11.205
  10 in total

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