Literature DB >> 25041277

Tramadol can selectively manage moderate pain in children following European advice limiting codeine use.

Pierluigi Marzuillo1, Lorenzo Calligaris2, Egidio Barbi2.   

Abstract

UNLABELLED: The European Medicine Agency recommendations limiting codeine use in children have created a void in managing moderate pain. We review the evidence on the pharmacokinetic, pharmacodynamic and safety profile of tramadol, a possible substitute for codeine.
CONCLUSION: Tramadol appears to be safe in both paediatric inpatients and outpatients. It may be appropriate to limit the current use of tramadol to monitored settings in children with risk factors for respiratory depression, subject to further safety evidence. ©2014 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  Codeine; Pain; Tramadol; Tramadol pharmacodinamic; Tramadol pharmacokinetic

Mesh：

Substances：

Year:  2014        PMID： 25041277     DOI： 10.1111/apa.12738

Source DB:  PubMed          Journal:  Acta Paediatr        ISSN： 0803-5253            Impact factor:   2.299


  4 in total

1.  Individual short-acting opioids and the risk of opioid-related adverse events in adolescents.

Authors:  Cecilia P Chung; Stephen Todd Callahan; William O Cooper; William D Dupont; Katherine T Murray; Andrew D Franklin; Kathi Hall; Judith A Dudley; Charles Michael Stein; Wayne A Ray
Journal:  Pharmacoepidemiol Drug Saf       Date:  2019-08-16       Impact factor: 2.890

2.  Analgesic Drug Prescription Patterns on Five International Paediatric Wards.

Authors:  Sebastian Botzenhardt; Asia N Rashed; Ian C K Wong; Stephen Tomlin; Antje Neubert
Journal:  Paediatr Drugs       Date:  2016-12       Impact factor: 3.022

3.  Tramadol vs dexmedetomidine for emergence agitation control in pediatric patients undergoing adenotonsillectomy with sevoflurane anesthesia: prospective randomized controlled clinical study.

Authors:  Nurdan Bedirli; Mehmet Akçabay; Ulku Emik
Journal:  BMC Anesthesiol       Date:  2017-03-11       Impact factor: 2.217

4.  Tramadol overdose and apnea in hospitalized children, a review of 20 cases.

Authors:  Hossein Hassanian-Moghaddam; Fariba Farnaghi; Mitra Rahimi
Journal:  Res Pharm Sci       Date:  2015 Nov-Dec
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.