OBJECTIVE: A foreign body giant cell (FBGC) reaction may occur in response to implanted xenogenic biomaterials. Here we report a FBGC reaction to the recently introduced xenogenic biomaterial, tarSys™, used for correction of lower eyelid retraction. METHOD: A retrospective chart review of two patients with FBGC reaction to tarSys™ implantation was performed. RESULTS: Two patients (aged 51, 58 year) with lower eyelid retraction underwent surgical implantation of tarSys™ spacer grafts for correction. Both patients subsequently experienced chronic swelling requiring graft removal. Examination of the specimens showed a palisading FBGC reaction around acellular pink fibrillar material. CONCLUSION: A FBGC reaction may follow implantation of the tarSys™ xenograft.
OBJECTIVE: A foreign body giant cell (FBGC) reaction may occur in response to implanted xenogenic biomaterials. Here we report a FBGC reaction to the recently introduced xenogenic biomaterial, tarSys™, used for correction of lower eyelid retraction. METHOD: A retrospective chart review of two patients with FBGC reaction to tarSys™ implantation was performed. RESULTS: Two patients (aged 51, 58 year) with lower eyelid retraction underwent surgical implantation of tarSys™ spacer grafts for correction. Both patients subsequently experienced chronic swelling requiring graft removal. Examination of the specimens showed a palisading FBGC reaction around acellular pink fibrillar material. CONCLUSION: A FBGC reaction may follow implantation of the tarSys™ xenograft.