Literature DB >> 25038789

Drug discovery: tools and rules for macrocycles.

Christian Heinis1.   

Abstract

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Year:  2014        PMID： 25038789     DOI： 10.1038/nchembio.1605

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


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  10 in total

Review 1.  Ribosomal production and in vitro selection of natural product-like peptidomimetics: the FIT and RaPID systems.

Authors:  Christopher J Hipolito; Hiroaki Suga
Journal:  Curr Opin Chem Biol       Date:  2012-03-06       Impact factor: 8.822

Review 2.  The design, structures and therapeutic potential of protein epitope mimetics.

Authors:  John A Robinson; Steve Demarco; Frank Gombert; Kerstin Moehle; Daniel Obrecht
Journal:  Drug Discov Today       Date:  2008-09-11       Impact factor: 7.851

Review 3.  Protein-protein interactions as druggable targets: recent technological advances.

Authors:  Alicia P Higueruelo; Harry Jubb; Tom L Blundell
Journal:  Curr Opin Pharmacol       Date:  2013-06-01       Impact factor: 5.547

Review 4.  Macrocyclic drugs and clinical candidates: what can medicinal chemists learn from their properties?

Authors:  Fabrizio Giordanetto; Jan Kihlberg
Journal:  J Med Chem       Date:  2013-09-17       Impact factor: 7.446

Review 5.  The exploration of macrocycles for drug discovery--an underexploited structural class.

Authors:  Edward M Driggers; Stephen P Hale; Jinbo Lee; Nicholas K Terrett
Journal:  Nat Rev Drug Discov       Date:  2008-07       Impact factor: 84.694

Review 6.  Contemporary strategies for peptide macrocyclization.

Authors:  Christopher J White; Andrei K Yudin
Journal:  Nat Chem       Date:  2011-06-23       Impact factor: 24.427

7.  Butelase 1 is an Asx-specific ligase enabling peptide macrocyclization and synthesis.

Authors:  Giang K T Nguyen; Shujing Wang; Yibo Qiu; Xinya Hemu; Yilong Lian; James P Tam
Journal:  Nat Chem Biol       Date:  2014-07-20       Impact factor: 15.040

8.  Phage-encoded combinatorial chemical libraries based on bicyclic peptides.

Authors:  Christian Heinis; Trevor Rutherford; Stephan Freund; Greg Winter
Journal:  Nat Chem Biol       Date:  2009-07       Impact factor: 15.040

9.  How proteins bind macrocycles.

Authors:  Elizabeth A Villar; Dmitri Beglov; Spandan Chennamadhavuni; John A Porco; Dima Kozakov; Sandor Vajda; Adrian Whitty
Journal:  Nat Chem Biol       Date:  2014-07-20       Impact factor: 15.040

10.  Comprehensive analysis of loops at protein-protein interfaces for macrocycle design.

Authors:  Jason Gavenonis; Bradley A Sheneman; Timothy R Siegert; Matthew R Eshelman; Joshua A Kritzer
Journal:  Nat Chem Biol       Date:  2014-07-20       Impact factor: 15.040
  10 in total
  25 in total

Review 1.  Arylation Chemistry for Bioconjugation.

Authors:  Chi Zhang; Ekaterina V Vinogradova; Alexander M Spokoyny; Stephen L Buchwald; Bradley L Pentelute
Journal:  Angew Chem Int Ed Engl       Date:  2019-02-15       Impact factor: 15.336

2.  Structural and conformational determinants of macrocycle cell permeability.

Authors:  Björn Over; Pär Matsson; Christian Tyrchan; Per Artursson; Bradley C Doak; Michael A Foley; Constanze Hilgendorf; Stephen E Johnston; Maurice D Lee; Richard J Lewis; Patrick McCarren; Giovanni Muncipinto; Ulf Norinder; Matthew W D Perry; Jeremy R Duvall; Jan Kihlberg
Journal:  Nat Chem Biol       Date:  2016-10-17       Impact factor: 15.040

3.  Sequence-defined bioactive macrocycles via an acid-catalysed cascade reaction.

Authors:  Mintu Porel; Dana N Thornlow; Ngoc N Phan; Christopher A Alabi
Journal:  Nat Chem       Date:  2016-05-09       Impact factor: 24.427

4.  Two-Step Synthesis of Complex Artificial Macrocyclic Compounds.

Authors:  Rudrakshula Madhavachary; Eman M M Abdelraheem; Arianna Rossetti; Aleksandra Twarda-Clapa; Bogdan Musielak; Katarzyna Kurpiewska; Justyna Kalinowska-Tłuścik; Tad A Holak; Alexander Dömling
Journal:  Angew Chem Int Ed Engl       Date:  2017-08-01       Impact factor: 15.336

5.  Dynamic covalent chemistry enables formation of antimicrobial peptide quaternary assemblies in a completely abiotic manner.

Authors:  James F Reuther; Justine L Dees; Igor V Kolesnichenko; Erik T Hernandez; Dmitri V Ukraintsev; Rusheel Guduru; Marvin Whiteley; Eric V Anslyn
Journal:  Nat Chem       Date:  2017-08-21       Impact factor: 24.427

6.  Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.

Authors:  Andrew L McIver; Weihe Zhang; Qingyang Liu; Xinpeng Jiang; Michael A Stashko; James Nichols; Michael J Miley; Jacqueline Norris-Drouin; Mischa Machius; Deborah DeRyckere; Edgar Wood; Douglas K Graham; H Shelton Earp; Dmitri Kireev; Stephen V Frye; Xiaodong Wang
Journal:  ChemMedChem       Date:  2017-01-09       Impact factor: 3.466

7.  Beyond cyclosporine A: conformation-dependent passive membrane permeabilities of cyclic peptide natural products.

Authors:  Christopher L Ahlbach; Katrina W Lexa; Andrew T Bockus; Valerie Chen; Phillip Crews; Matthew P Jacobson; R Scott Lokey
Journal:  Future Med Chem       Date:  2015-06-12       Impact factor: 3.808

8.  Peptide macrocyclization catalyzed by a prolyl oligopeptidase involved in α-amanitin biosynthesis.

Authors:  Hong Luo; Sung-Yong Hong; R Michael Sgambelluri; Evan Angelos; Xuan Li; Jonathan D Walton
Journal:  Chem Biol       Date:  2014-12-04

9.  Towards vast libraries of scaffold-diverse, conformationally constrained oligomers.

Authors:  Thomas Kodadek; Patrick J McEnaney
Journal:  Chem Commun (Camb)       Date:  2016-03-21       Impact factor: 6.222

10.  Harnessing solid-state packing for selective detection of chloride in a macrocyclic anionophore.

Authors:  Chris L Vonnegut; Airlia M Shonkwiler; Lev N Zakharov; Michael M Haley; Darren W Johnson
Journal:  Chem Commun (Camb)       Date:  2016-07-21       Impact factor: 6.222
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