Literature DB >> 25038622

Functional significance of long non-coding RNAs in breast cancer.

Rajeev Vikram1, Rahul Ramachandran, Khaja Shameem Mohammed Abdul.   

Abstract

Most of the genome is transcribed to transcripts of no protein-coding potential. However, these transcripts do not represent transcriptional 'noise', rather they play an important role in cellular metabolism and development. Non-coding transcripts of 200 bases to 100 kb length are termed as long non-coding RNAs, majority of which are yet to be characterised thoroughly. Long non-coding RNAs (lncRNAs) play a significant role in cellular process ranging from transcriptional to post-transcriptional regulation. In this review, we highlight the recent efforts to characterise the major functions of lncRNAs in breast cancer. lncRNA expression is altered in several cancer types. Further, the aberrant regulation of lncRNAs promotes tumour development as they are involved in several cancer-associated pathways.

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Year:  2014        PMID： 25038622     DOI： 10.1007/s12282-014-0554-y

Source DB:  PubMed          Journal:  Breast Cancer        ISSN： 1340-6868            Impact factor:   4.239


  37 in total

1.  LncRNAs BCYRN1 promoted the proliferation and migration of rat airway smooth muscle cells in asthma via upregulating the expression of transient receptor potential 1.

Authors:  Xiao-Yu Zhang; Luo-Xian Zhang; Cui-Jie Tian; Xue-Yi Tang; Li-Min Zhao; Ya-Li Guo; Dong-Jun Cheng; Xian-Liang Chen; Li-Jun Ma; Zhuo-Chang Chen
Journal:  Am J Transl Res       Date:  2016-08-15       Impact factor: 4.060

Review 2.  Noncoding RNAs in breast cancer.

Authors:  Pang-Kuo Lo; Benjamin Wolfson; Xipeng Zhou; Nadire Duru; Ramkishore Gernapudi; Qun Zhou
Journal:  Brief Funct Genomics       Date:  2015-12-18       Impact factor: 4.241

3.  Screening of miRNAs associated with lymph node metastasis in Her-2-positive breast cancer and their relationship with prognosis.

Authors:  En-Qi Qiao; Hong-Jian Yang; Xi-Ping Zhang
Journal:  J Zhejiang Univ Sci B       Date:  2020-06       Impact factor: 3.066

Review 4.  The role of lncRNAs in the development of endometrial carcinoma.

Authors:  Bi-Lan Li; Xiao-Ping Wan
Journal:  Oncol Lett       Date:  2018-07-04       Impact factor: 2.967

5.  Long non-coding RNA MALAT1 promotes proliferation and suppresses apoptosis of glioma cells through derepressing Rap1B by sponging miR-101.

Authors:  Zhenjiang Li; Chenyang Xu; Bingqian Ding; Ming Gao; Xinting Wei; Nan Ji
Journal:  J Neurooncol       Date:  2017-05-27       Impact factor: 4.130

6.  MALAT1/miR-124/Capn4 axis regulates proliferation, invasion and EMT in nasopharyngeal carcinoma cells.

Authors:  Baoyuan Shi; Yandan Wang; Fengfang Yin
Journal:  Cancer Biol Ther       Date:  2017-08-31       Impact factor: 4.742

7.  Mammary Tumor-Associated RNAs Impact Tumor Cell Proliferation, Invasion, and Migration.

Authors:  Sarah D Diermeier; Kung-Chi Chang; Susan M Freier; Junyan Song; Osama El Demerdash; Alexander Krasnitz; Frank Rigo; C Frank Bennett; David L Spector
Journal:  Cell Rep       Date:  2016-09-27       Impact factor: 9.423

8.  Long noncoding RNA NEAT1 promotes the metastasis of osteosarcoma via interaction with the G9a-DNMT1-Snail complex.

Authors:  Yong Li; Cai Cheng
Journal:  Am J Cancer Res       Date:  2018-01-01       Impact factor: 6.166

Review 9.  A brief review on long noncoding RNAs: a new paradigm in breast cancer pathogenesis, diagnosis and therapy.

Authors:  Sara Malih; Massoud Saidijam; Narges Malih
Journal:  Tumour Biol       Date:  2015-12-11

10.  FAM83A-AS1 promotes lung adenocarcinoma cell migration and invasion by targeting miR-150-5p and modifying MMP14.

Authors:  Guodong Xiao; Peili Wang; Xiaoqiang Zheng; Dapeng Liu; Xin Sun
Journal:  Cell Cycle       Date:  2019-09-16       Impact factor: 4.534
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