Literature DB >> 25038324

The effect of the uncertainty in the number of contributors to mixed DNA profiles on profile interpretation.

Jo-Anne Bright1, James M Curran2, John S Buckleton3.   

Abstract

The effect of uncertainty in the number of contributors to a profile is a matter of some contention in forensic DNA interpretation. Interpretation methods are moving towards continuous models. Within this paper the effect of misspecification of the number of contributors to a profile caused by one artefactual peak, either a large back stutter or a forward stutter, was investigated using a continuous model. The misassignment of the number of contributors to a profile either has no significant effect or decreases the LR for the true contributors. It often increases the chance of an adventitious link.
Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Forensic DNA; Identifiler; Interpretation; Mixed DNA profiles; STRmix™

Mesh:

Substances:

Year:  2014        PMID: 25038324     DOI: 10.1016/j.fsigen.2014.06.009

Source DB:  PubMed          Journal:  Forensic Sci Int Genet        ISSN: 1872-4973            Impact factor:   4.882


  5 in total

1.  MaSTR™: an effective probabilistic genotyping tool for interpretation of STR mixtures associated with differentially degraded DNA.

Authors:  Mitchell M Holland; Teresa M Tiedge; Abigail J Bender; Sidney A Gaston-Sanchez; Jennifer A McElhoe
Journal:  Int J Legal Med       Date:  2022-01-29       Impact factor: 2.686

2.  Four model variants within a continuous forensic DNA mixture interpretation framework: Effects on evidential inference and reporting.

Authors:  Harish Swaminathan; Muhammad O Qureshi; Catherine M Grgicak; Ken Duffy; Desmond S Lun
Journal:  PLoS One       Date:  2018-11-20       Impact factor: 3.240

3.  Revisiting single cell analysis in forensic science.

Authors:  Davis R L Watkins; Dan Myers; Hannah E Xavier; Michael A Marciano
Journal:  Sci Rep       Date:  2021-03-29       Impact factor: 4.379

Review 4.  A Review of Probabilistic Genotyping Systems: EuroForMix, DNAStatistX and STRmix™.

Authors:  Peter Gill; Corina Benschop; John Buckleton; Øyvind Bleka; Duncan Taylor
Journal:  Genes (Basel)       Date:  2021-09-30       Impact factor: 4.096

5.  Internal Validation of MaSTR™ Probabilistic Genotyping Software for the Interpretation of 2-5 Person Mixed DNA Profiles.

Authors:  Michael S Adamowicz; Taylor N Rambo; Jennifer L Clarke
Journal:  Genes (Basel)       Date:  2022-08-11       Impact factor: 4.141

  5 in total

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