Literature DB >> 25037707

Androgen actions in the ovary: balance is key.

Hen Prizant1, Norbert Gleicher1, Aritro Sen2.   

Abstract

For many decades, elevated androgens in women have been associated with poor reproductive health. However, recent studies have shown that androgens play a crucial role in women's fertility. The following review provides an overall perspective about how androgens and androgen receptor-mediated actions regulate normal follicular development, as well as discuss emerging concepts, latest perceptions, and controversies regarding androgen actions and signaling in the ovary.
© 2014 Society for Endocrinology.

Entities:  

Keywords:  androgen; androgen receptor; female reproduction; ovary

Mesh:

Substances:

Year:  2014        PMID: 25037707     DOI: 10.1530/JOE-14-0296

Source DB:  PubMed          Journal:  J Endocrinol        ISSN: 0022-0795            Impact factor:   4.286


  42 in total

1.  Suspected ontogeny of a recently described hypo-androgenic PCOS-like phenotype with advancing age.

Authors:  Norbert Gleicher; Vitaly A Kushnir; Sarah K Darmon; Qi Wang; Lin Zhang; David F Albertini; David H Barad
Journal:  Endocrine       Date:  2018-01-06       Impact factor: 3.633

2.  Finding the Right Balance: Androgens at the Tipping Point of Fertility and Metabolism in Women.

Authors:  Michael T Sellix; Aritro Sen
Journal:  Endocrinology       Date:  2017-03-01       Impact factor: 4.736

3.  First ovarian response to gonadotrophin stimulation in rats exposed to neonatal androgen excess.

Authors:  Rebeca Chávez-Genaro; Gabriel Anesetti
Journal:  J Mol Histol       Date:  2018-10-09       Impact factor: 2.611

4.  Androgens Regulate Ovarian Gene Expression Through Modulation of Ezh2 Expression and Activity.

Authors:  Xiaoting Ma; Emily Hayes; Anindita Biswas; Christina Seger; Hen Prizant; Stephen R Hammes; Aritro Sen
Journal:  Endocrinology       Date:  2017-09-01       Impact factor: 4.736

5.  CRISPR Fish Reel in Novel Roles for Estrogen Receptors in Reproduction.

Authors:  Jessica Y Hsu; Matthew J Sikora
Journal:  Endocrinology       Date:  2017-07-01       Impact factor: 4.736

6.  Effects of dehydroepiandrosterone (DHEA) supplementation on sexual function in premenopausal infertile women.

Authors:  Vitaly A Kushnir; Sarah K Darmon; David H Barad; Andrea Weghofer; Norbert Gleicher
Journal:  Endocrine       Date:  2018-10-11       Impact factor: 3.633

Review 7.  Genetics of androgen metabolism in women with infertility and hypoandrogenism.

Authors:  Aya Shohat-Tal; Aritro Sen; David H Barad; Vitaly Kushnir; Norbert Gleicher
Journal:  Nat Rev Endocrinol       Date:  2015-05-05       Impact factor: 43.330

8.  Effects of an Environmentally Relevant Phthalate Mixture on Cultured Mouse Antral Follicles.

Authors:  Changqing Zhou; Jodi A Flaws
Journal:  Toxicol Sci       Date:  2017-03-01       Impact factor: 4.849

9.  Histone demethylase KDM4A and KDM4B expression in granulosa cells from women undergoing in vitro fertilization.

Authors:  Adam J Krieg; Sarah R Mullinax; Frances Grimstad; Kaitlin Marquis; Elizabeth Constance; Yan Hong; Sacha A Krieg; Katherine F Roby
Journal:  J Assist Reprod Genet       Date:  2018-03-14       Impact factor: 3.412

Review 10.  The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited.

Authors:  Robert L Rosenfield; David A Ehrmann
Journal:  Endocr Rev       Date:  2016-07-26       Impact factor: 19.871

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