INTRODUCTION AND OBJECTIVES: Percutaneous paravalvular leak closure is a complex procedure with varying success rates; the lack of closure devices specifically designed for this purpose has hampered this technique. The characteristics of the Amplatzer Vascular Plug III appear to be well suited for paravalvular leak closures; however, the available data are limited to case reports or small series of patients. The aim of this study was to analyze the feasibility and efficacy of paravalvular leak with this device. METHODS: The immediate and 90-day safety and efficacy of mitral and aortic paravalvular leak closures performed with this device at our hospital were analyzed. RESULTS: Percutaneous repair of 34 paravalvular leaks (27 mitral, 7 aortic) was attempted in 33 patients. The device was successfully implanted in 93.9% (in 2 patients, a second planned procedure was needed), and successful closure (defined as regurgitation reduction ≥ 1 grade) was achieved in 90.9% of patients. Complications included emergency surgery due to disc interference (n=1) and blood transfusion (n=3). There were no reports of procedure-related death, myocardial infarction, or stroke. At 90 days, survival was 100%, and 90.3% of patients showed significant clinical improvement; 4 patients developed vascular complications (pseudoaneurysm). CONCLUSIONS: Mitral and aortic paravalvular leak closure with the Amplatzer Vascular Plug III is feasible and safe, with high clinical and echocardiographic success rates.
INTRODUCTION AND OBJECTIVES: Percutaneous paravalvular leak closure is a complex procedure with varying success rates; the lack of closure devices specifically designed for this purpose has hampered this technique. The characteristics of the Amplatzer Vascular Plug III appear to be well suited for paravalvular leak closures; however, the available data are limited to case reports or small series of patients. The aim of this study was to analyze the feasibility and efficacy of paravalvular leak with this device. METHODS: The immediate and 90-day safety and efficacy of mitral and aortic paravalvular leak closures performed with this device at our hospital were analyzed. RESULTS: Percutaneous repair of 34 paravalvular leaks (27 mitral, 7 aortic) was attempted in 33 patients. The device was successfully implanted in 93.9% (in 2 patients, a second planned procedure was needed), and successful closure (defined as regurgitation reduction ≥ 1 grade) was achieved in 90.9% of patients. Complications included emergency surgery due to disc interference (n=1) and blood transfusion (n=3). There were no reports of procedure-related death, myocardial infarction, or stroke. At 90 days, survival was 100%, and 90.3% of patients showed significant clinical improvement; 4 patients developed vascular complications (pseudoaneurysm). CONCLUSIONS:Mitral and aortic paravalvular leak closure with the Amplatzer Vascular Plug III is feasible and safe, with high clinical and echocardiographic success rates.
Authors: Grzegorz Smolka; Piotr Pysz; Michał Kozłowski; Marek Jasiński; Radosław Gocoł; Tomasz Roleder; Agnieszka Kargul; Andrzej Ochała; Wojciech Wojakowski Journal: Postepy Kardiol Interwencyjnej Date: 2016-05-11 Impact factor: 1.426
Authors: Grzegorz Smolka; Piotr Pysz; Andrzej Ochała; Michał Kozłowski; Wojciech Zasada; Zofia Parma; Michał Tendera; Wojciech Wojakowski Journal: Arch Med Sci Date: 2016-06-13 Impact factor: 3.318
Authors: I Cruz-Gonzalez; J C Rama-Merchan; J Rodríguez-Collado; J Martín-Moreiras; A Diego-Nieto; M Barreiro-Pérez; P L Sánchez Journal: Neth Heart J Date: 2017-02 Impact factor: 2.380
Authors: Piotr Pysz; Michał Kozłowski; Magdalena Malczewska; Eliza Adamczyk-Filipek; Wojciech Wojakowski; Grzegorz Smolka Journal: Postepy Kardiol Interwencyjnej Date: 2019-06-26 Impact factor: 1.426